WD2000-012547
WD2000-012547 is a selective poly(ADP-ribose)-polymerase (PARP-1) inhibitor with a pKi of 8.221.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 283172-68-9
- Fòrmula: C17H14N2O
- Peso molecular:262.31
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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PARP-1 8.221 (pKi) |
Poly(ADP-ribose) polymerase-1 (PARP-1) functions as a DNA damage sensor and signaling molecule. It plays a vital role in the repair of DNA strand breaks induced by radiation and chemotherapeutic drugs; inhibitors of this enzyme have the potential to improve cancer chemotherapy or radiotherapy. WD2000-012547 (Compound 66) is a representative PARP-1 inhibitor with a pKi of 8.221[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 283172-68-9
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Peso molecular 262.31
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Fòrmula C17H14N2O
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SMILES
O=C(NCC1)C2=CC=CC3=C2C1=C(C4=CC=CC=C4)N3
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
WD2000-012547 Related Classifications
HY-U00223 Related Classifications
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