Baminercept
Based on 3 publication(s) in Google Scholar
Baminercept (BG 9924; TT-47) is an Ig fusion protein targeting the lymphotoxin β receptor (LTβR). Baminercept effectively regulates subsets of circulating immune cells by inhibiting LIGHT, LT-α1β2 and their receptors. Baminercept also increases blood lymphocyte counts and reduces plasma CXCL13 levels. Baminercept carries a high risk of hepatotoxicity. Baminercept can be used in research on rheumatoid arthritis and primary Sjögren's syndrome.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 99.97%
- No. CAS: 909110-25-4
- Peso molecular:93.76 kDa
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications Citing Use of MedChemExpress (MCE) Baminercept
MoreVer todos los productos específicos de isoformas TNF Receptor
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Actividad biológica
Descripciòn
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Ensayo clínico
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Conjugated
Unconjugated
Reconsititution
The product can be reconstituted/diluted with sterile PBS or saline.
Format
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[LTBR (lymphotoxin beta receptor, TNFRSF3, tumor necrosis factor receptor superfamily (TNFR)member 3, TNFCR)]2-IGHG1 Fc (Fragment constant)
Aplicación
ELISA, FACS, Functional assay
Verified Bioactivity
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Immobilized TNF-beta/TNFSF1 Protein, Human (HY-P7304) can bind Baminercept. The EC50 for this effect is 16.53 ng/mL.
Chemical Information
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No. CAS 909110-25-4
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Appearance Liquid
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Peso molecular 93.76 kDa
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Color Colorless to light yellow
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SMILES
[Baminercept]
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Synonyms
BG 9924; TT-47
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Envío
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (3)
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Journal Impact Factor
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Most Recent
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Nat Biotechnol
2025 Oct 17. PMID: 41107533 -
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Pureza y Documentación
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Ficha de datos (258 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)