DC_C66
DC_C66 is a cell-permeable, selective coactivator associated arginine methyltransferase 1 (CARM1) inhibitor with an IC50 of 1.8 μM. DC_C66 has a good selectivity for CARM1 against PRMT1 (IC50=21 μM), PRMT6 (IC50= 47μM), and PRMT5.
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- No. CAS: 108181-00-6
- Fòrmula: C28H22NO2+
- Peso molecular:404.48
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Chemical Information
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Actividad biológica
Descripciòn
IC50 & Target
IC50: 1.8 μM (CARM1)[1]
In Vitro
DC_C66 (6.25-100 μM; 24-72 hours) exhibits antiproliferation activity in several CARM1-associated cancer cell lines[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
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Cell Line:HELA, K562, MCF7 cells
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Concentration:6.25, 12.5, 25, 50, 100 μM
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Incubation Time:24, 48, 72 hours
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Result:Inhibits proliferation of cancer cells in a time-dependent and dose-dependent manner in HELA, K562, and MCF7 cells.
Chemical Information
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No. CAS 108181-00-6
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Peso molecular 404.48
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Fòrmula C28H22NO2+
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SMILES
O=C(OCC)C1=[N+]2C(C(C=CC=C3)=C3CC2)=CC4=C1C(C=CC=C5)=C5C6=C4C=CC=C6
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DC_C66 Related Classifications
HY-100855 Related Classifications
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