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Referencia número: HY-155613

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M867

M867 is a selective and reversible inhibitor of caspase-3 with an IC₅₀ of 1.4 nM and K_i of 0.7 nM. M867 has anti apoptotic activity.

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No. CAS: 680999-39-7
Fòrmula: C₂₇H₄₃N₇O₆
Peso molecular:561.67

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

M867 Chemical Structure

No. CAS: 680999-39-7

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
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- IC₅₀ & Target
Chemical Information
Pureza y Documentación
Referencias
Calculators
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Actividad biológica

Descripciòn

M867 is a selective and reversible inhibitor of caspase-3 with an IC₅₀ of 1.4 nM and K_i of 0.7 nM. M867 has anti apoptotic activity^[1].

IC₅₀ & Target

Caspase 3

Ver todos los productos específicos de isoformas Caspase :

Chemical Information

No. CAS 680999-39-7
Peso molecular 561.67
Fòrmula C₂₇H₄₃N₇O₆
SMILES

O=C1N(C=C(N=C1NCC2=NON=C2C)C(C)(C)C)[C@H](C(N[C@H](C(CN(CCCCC)C)=O)CC(O)=O)=O)CC
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Han Y, et.al. Novel pyrazinone mono-amides as potent and reversible caspase-3 inhibitors. Bioorg Med Chem Lett. 2005 Feb 15;15(4):1173-80. [Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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M867

Ver todos los productos específicos de isoformas Caspase