MPT0G413
MPT0G413 (Compound 6) is a potent, selective, orally active and brain-penetrant HDAC6 inhibitor with an IC50 of 3.92 nM. MPT0G413 decreases not only the level of phosphorylation of tau proteins but also the aggregation of tau proteins. MPT0G413 can ameliorate the impaired learning and memory. MPT0G413 can be used for the research of neurological disease, such as Alzheimer's disease.
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- No. CAS: 2241643-23-0
- Fòrmula: C24H20N2O4
- Peso molecular:400.43
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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HDAC6 3.92 nM (IC50) |
Chemical Information
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No. CAS 2241643-23-0
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Peso molecular 400.43
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Fòrmula C24H20N2O4
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SMILES
O=C(NO)C1=CC=C(CN2C=CC3=C2C=CC(C(C4=CC=C(OC)C=C4)=O)=C3)C=C1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MPT0G413 Related Classifications
HY-141541 Related Classifications
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