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Referencia número: HY-115525

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NBUMP

NBUMP is a 5-HT₁A receptor ligand with a 5-HT₁A receptor K_i of 0.1 nM, α₁-adrenergic receptor K_i of 46 nM, and a 5-HT₁A receptor-to-α₁-adrenergic receptor selectivity ratio of 460.NBUMP binds to the 5-HT₁A receptor with high affinity.NBUMP binds to the α₁-adrenergic receptor with lower affinity.

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No. CAS: 1348755-27-0
Fòrmula: C₂₆H₃₉N₃O₂
Peso molecular:425.62

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

NBUMP Chemical Structure

No. CAS: 1348755-27-0

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- IC₅₀ & Target
Chemical Information
Pureza y Documentación
Referencias
Calculators
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Actividad biológica

Descripciòn

IC₅₀ & Target^[1]

5-HT_1A Receptor

0.1 nM (Ki)

A₁AR

46 nM (Ki)

Ver todos los productos específicos de isoformas 5-HT Receptor :

Ver todos los productos específicos de isoformas Adenosine Receptor :

Chemical Information

No. CAS 1348755-27-0
Peso molecular 425.62
Fòrmula C₂₆H₃₉N₃O₂
SMILES

O=C(NCCCCN1CCN(C=2C=CC=CC2OC)CC1)C3C4CC5CC(C4)CC3C5
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Instrucciones de manejo (2659 KB)

Referencias

[1]. Lopez-Rodriguez M L, et al. Arylpiperazine derivatives acting at 5-HT1A receptors[J]. Current medicinal chemistry, 2002, 9(4): 443-469.

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Actividad biológica
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- IC₅₀ & Target
Chemical Information
Pureza y Documentación
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NBUMP

Ver todos los productos específicos de isoformas 5-HT Receptor

Ver todos los productos específicos de isoformas Adenosine Receptor

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

NBUMP Related Classifications

HY-115525 Related Classifications