Me3 - malic enzyme 3, NADP(+)-dependent, mitochondrial Gene

Also Known as 1700020C08Rik; B230207H15Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 109264

Summary

Predicted to enable NADP+ binding activity and malate dehydrogenase (decarboxylating) (NADP+) activity. Predicted to be involved in malate metabolic process and pyruvate metabolic process. Located in mitochondrion. Is expressed in several structures, including alimentary system; central nervous system; integumental system; metanephros; and sensory organ. Orthologous to human ME3 (malic enzyme 3). [provided by Alliance of Genome Resources, Apr 2022]

Me3 Products (1)

mRNA Protein Name
NM_181407.4 NP_852072.2 NADP-dependent malic enzyme, mitochondrial

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables malate dehydrogenase (decarboxylating) (NADP+) activity IDA
IDA: Inferred from direct assay
25711 MGI
Biological Process GO Annotation Evidence References Source
involved in pyruvate metabolic process IDA
IDA: Inferred from direct assay
25711 MGI
Cellular Component GO Annotation Evidence References Source
is active in mitochondrial matrix IDA
IDA: Inferred from direct assay
25711 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

NADP-dependent malic enzyme, mitochondrial

  • NADP-ME

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-153191 EZH2-IN-15 Inhibitor 99.18% Phase 3
HY-159834 Progerinin Inhibitor 99.74% Phase 2

Pre-clinical Phase

Bioactive Molecules (79)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-15648B GSK-J4 99.67% Unkown
HY-100421 CPI-455 Inhibitor 98.95% Unkown
HY-101117 EED226 Inhibitor 99.56% Unkown
HY-12583 A-366 Inhibitor 98.84% Unkown
HY-15648F GSK-J4 hydrochloride Inhibitor 99.01% Unkown
HY-150190 F5446 99.73% Unkown
HY-15648 GSK-J1 Inhibitor 99.94% Unkown
HY-120400 KDM5-C70 Inhibitor 98.82% Unkown
HY-130708 UNC6852 Inhibitor 98.49% Unkown
HY-N7404 Nε,Nε,Nε-Trimethyllysine chloride 99.14% Unkown
HY-16705 BRD4770 Inhibitor 99.79% Unkown
HY-148334 MS8815 Degrader 99.95% Unkown
HY-119344 MS37452 Inhibitor 99.81% Unkown
HY-100014 KDM5A-IN-1 Inhibitor 99.64% Unkown
HY-148458 EZH2-IN-14 Inhibitor 98.06% Unkown
HY-100421A CPI-455 hydrochloride Inhibitor 99.95% Unkown
HY-138691A JQKD82 trihydrochloride Inhibitor 99.89% Unkown
HY-66026 Fmoc-Lys(Me)3-OH Chloride 98.60% Unkown
HY-N7404S Nε,Nε,Nε-Trimethyllysine-d9 chloride / Unkown
HY-125837A MS31 trihydrochloride Inhibitor 98.0% Unkown
HY-125292 NV03 Antagonist 99.77% Unkown
HY-158432 GT-653 Degrader 99.84% Unkown
HY-132896 KDM4-IN-3 Inhibitor 99.36% Unkown
HY-15648A GSK-J2 Control 99.75% Unkown
HY-150249 GSK3735967 Inhibitor 99.34% Unkown
HY-N0857 Deoxyandrographolide Activator 99.80% Unkown
HY-100764 YUKA1 Inhibitor 99.15% Unkown
HY-126327A UNC4976 TFA Antagonist 95.59% Unkown
HY-P2254 H3K27(Me3) (15-34) 96.87% Unkown
HY-P2255 H3K4(Me) (1-20) 99.87% Unkown
HY-W051391 1,4,7-Trimethyl-1,4,7-triazonane 98.50% Unkown
HY-15648D GSK-J1 lithium salt Inhibitor 98.33% Unkown
HY-126327 UNC4976 Antagonist / Unkown
HY-125837 MS31 Inhibitor / Unkown
HY-120766 NCDM-32B Inhibitor 97.0% Unkown
HY-P10463A ssK36 TFA Inhibitor 99.34% Unkown
HY-P2257 H3K4(Me3) (1-20) 98.69% Unkown
HY-W100209 5Me3F4AP Inhibitor 99.55% Unkown
HY-W274807 TM-2-51 / Unkown
HY-169061 WQQ-345 / Unkown
HY-121511 EML631 Inhibitor / Unkown
HY-122595 EZH2-IN-1 Inhibitor / Unkown
HY-122640 NPD13668 Inhibitor / Unkown
HY-138691 JQKD82 Inhibitor / Unkown
HY-143616 EZH2-IN-7 Inhibitor / Unkown
HY-150619 KDM4-IN-4 Inhibitor / Unkown
HY-154599 5-Me-3’-dU-2’-phosphoramidite / Unkown
HY-156292 IHMT-EZH2-426 Inhibitor / Unkown
HY-15648G GSK-J1 sodium Inhibitor / Unkown
HY-15648I GSK-J2 sodium Inhibitor / Unkown
HY-162601 D-01 Inhibitor / Unkown
HY-168131 PROTAC EZH2 Degrader-3 / Unkown
HY-169375 RSL3-4-Me Control / Unkown
HY-171338 Gallocatechin-3-O-(3″-O-methyl)-gallate Inhibitor / Unkown
HY-174397 EED-IN-3 Inhibitor / Unkown
HY-178694 DC-PRC2in-01 Inhibitor / Unkown
HY-179446 HP1-IN-2 Inhibitor / Unkown
HY-179499 PROTAC EZH2 Degrader-9 / Unkown
HY-181089 CBX2-IN-1 Inhibitor / Unkown
HY-181413 PROTAC EZH2 Degrader-44 / Unkown
HY-181914 UNC7242 Antagonist / Unkown
HY-182365 EED-IN-4 Inhibitor / Unkown
HY-182366 EED-IN-5 Inhibitor / Unkown
HY-182448 TDI-11904 Inhibitor / Unkown
HY-182676 DC541 Inhibitor / Unkown
HY-183602 FRC-303 Inhibitor / Unkown
HY-183603 FRC-222 Inhibitor / Unkown
HY-184270 YM1240 / Unkown
HY-P10111A Histone H3K9me3 (1-15) TFA / Unkown
HY-P2252 H3K27(Me) (15-34) / Unkown
HY-P2253 H3K27(Me2) (15-34) / Unkown
HY-RS08272 ME3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-106258 Atilmotin Agonist / Unkown
HY-138691B JQKD82 dihydrochloride Inhibitor / Unkown
HY-169919 HDM-IN-1 Inhibitor / Unkown
HY-182962 7-Methylguanosine 5-disphosphoimidazolide disodium / Unkown
HY-P10463 ssK36 Inhibitor / Unkown
HY-RS19564 Me3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26060 Me3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Me3 NCBI NCBI:10873