Eed - embryonic ectoderm development Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 293104

Summary

Enables chromatin binding activity. Involved in negative regulation of transcription by RNA polymerase II and spinal cord development. Located in nucleus. Used to study transient cerebral ischemia. Orthologous to human EED (embryonic ectoderm development). [provided by Alliance of Genome Resources, Apr 2022]

Eed Products (1)

mRNA Protein Name
NM_001106278.2 NP_001099748.1 polycomb protein EED

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables chromatin binding IDA
IDA: Inferred from direct assay
23354331 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
24007266 RGD
Biological Process GO Annotation Evidence References Source
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
23354331 RGD
involved in spinal cord development IEP
IEP: Inferred from expression pattern
20515739 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

polycomb protein EED

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Phase
HY-139400A Pociredir hydrochloride Inhibitor 99.89% Phase 2
HY-158102 Rinzimetostat Inhibitor 99.90% Phase 1
HY-103663 MAK683 Inhibitor 99.02% Phase 1
HY-132922 EEDi-5273 Inhibitor 99.48% Phase 1

Pre-clinical Phase

Bioactive Molecules (46)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-101117 EED226 Inhibitor 99.56% Unkown
HY-130708 UNC6852 Inhibitor 98.49% Unkown
HY-101512 A-395 Inhibitor 99.12% Unkown
HY-139400 Pociredir Inhibitor 99.97% Unkown
HY-148334 MS8815 Degrader 99.95% Unkown
HY-W004697 Boc-GABA-OH 99.14% Unkown
HY-W014099 Boc-NH-C4-acid 99.65% Unkown
HY-130615 PROTAC EED degrader-2 Inhibitor 99.90% Unkown
HY-130979 EED226-COOH Degrader 99.88% Unkown
HY-130815A MAK683-C2-acid hydrochloride Inhibitor 99.60% Unkown
HY-136977 EEDi-5285 Inhibitor 99.87% Unkown
HY-160924 MS147 Degrader 98.31% Unkown
HY-130614 PROTAC EED degrader-1 Inhibitor 99.18% Unkown
HY-158239 MS181 98.36% Unkown
HY-135045 (S,R,S)-AHPC-C4-COOH 95.92% Unkown
HY-158102A Rinzimetostat TFA 99.82% Unkown
HY-132970 EED ligand 1 Inhibitor 99.93% Unkown
HY-130815 MAK683-CH2CH2COOH Inhibitor / Unkown
HY-114176B (S,R,S)-AHPC-C4-NH2 dihydrochloride / Unkown
HY-130816 (S,R,S)-AHPC-O-Ph-PEG1-NH2 96.97% Unkown
HY-114176 (S,R,S)-AHPC-C4-NH2 hydrochloride 99.69% Unkown
HY-P2266 SAH-EZH2 Inhibitor 99.50% Unkown
HY-RS04173 EED Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-103663A MAK683 hydrochloride Inhibitor / Unkown
HY-130711A (S,R,S)-AHPC-C3-NH2 TFA / Unkown
HY-114176A (S,R,S)-AHPC-C4-NH2 / Unkown
HY-130638 (S,R,S)-AHPC-O-Ph-PEG1-NH-Boc / Unkown
HY-130711 (S,R,S)-AHPC-C3-NH2 / Unkown
HY-101512D rel-A-395 hydrochloride Inhibitor / Unkown
HY-130637 Boc-NH-PEG1-Ph-O-CH2COOH / Unkown
HY-130711C (S,R,S)-AHPC-C3-NH2 dihydrochloride 95.0% Unkown
HY-148641 ZJH-16 Inhibitor / Unkown
HY-168131 PROTAC EZH2 Degrader-3 / Unkown
HY-174372 EZH2-IN-23 Inhibitor / Unkown
HY-174397 EED-IN-3 Inhibitor / Unkown
HY-178694 DC-PRC2in-01 Inhibitor / Unkown
HY-181308 PROTAC EZH2 Degrader-13 Degrader / Unkown
HY-181320 PROTAC EZH2 Degrader-19 Degrader / Unkown
HY-181323 PROTAC EZH2 Degrader-22 Degrader / Unkown
HY-181392 PROTAC EZH2 Degrader-35 Degrader / Unkown
HY-181413 PROTAC EZH2 Degrader-44 / Unkown
HY-182365 EED-IN-4 Inhibitor / Unkown
HY-182366 EED-IN-5 Inhibitor / Unkown
HY-124660A A-395N / Unkown
HY-RS16662 Eed Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23097 Eed Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Eed NCBI NCBI:8726