CD28 - CD28 molecule Gene

Canis lupus familiaris (sub-species: familiaris)

Gene ID: 403646 | Gene type: protein coding

About CD28

Primary_assembly 37: 12,440,613-12,471,203 forward strand.ROS_Cfam_1.0:CM025136.1

This gene has 3 transcripts (splice variants), 132 orthologues and 1 paralogue.

mRNA	Protein	Name
NM_001003087.2	NP_001003087.2	T-cell-specific surface glycoprotein CD28 precursor

Protein Preferred Names

Protein Names

T-cell-specific surface glycoprotein CD28

CD28 antigen (Tp44)	T-cell costimulatory molecule CD28
cell surface protein	costimulatory molecule B7 receptor CD28

Cat. No.	Product Name	Accession	Purity
HY-P77621	CD28 Protein, Canine (HEK293, His)	Q9GKP3 (T18-P153)	≥95%
HY-P77622	CD28 Protein, Canine (HEK293, mFc)	Q9GKP3 (T18-P153)	≥95%

Clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P1698	Reltecimod	Antagonist	/	Phase 3

Inhibitory Antibodies (5)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P99961	Tifcemalimab	Inhibitor	95.00%	Phase 3
HY-P99293	Galiximab	Inhibitor	99.23%	Phase 3
HY-P99302	Lulizumab	Inhibitor	≥95.0%	Phase 2
HY-P99420	Acazicolcept	Antagonist	99.27%	Phase 2
HY-P99717	Lulizumab pegol	Antagonist	/	Phase 2

Pre-clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-102090	B7/CD28 interaction inhibitor 1		99.47%	Unkown
HY-P1698B	Reltecimod TFA	Chemical	99.78%	Unkown
HY-N10445	Maydispenoid A		/	Unkown
HY-N10446	Maydispenoid B		/	Unkown

Inhibitory Antibodies (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P9975	Theralizumab	Agonist	97.21%	Unkown
HY-P99123	Anti-Mouse CD28 Antibody (37.51)		≥95.0%	Unkown

Species	Symbol	Source	ID
Homo sapiens	CD28	NCBI	NCBI:940
Macaca fascicularis	CD28	NCBI	NCBI:102146670
Mus musculus	CD28	NCBI	NCBI:12487
Rattus norvegicus	CD28	NCBI	NCBI:25660
Macaca mulatta	CD28	NCBI	NCBI:705313

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