PDK1 - pyruvate dehydrogenase kinase 1 Gene

Species: Canis lupus familiaris (sub-species: familiaris)

Gene Type: protein coding
Gene ID: 476828

About PDK1

Primary_assembly 36: 17,044,626-17,074,144 forward strand.ROS_Cfam_1.0:CM025135.1

This gene has 2 transcripts (splice variants), 208 orthologues and 4 paralogues.

PDK1 Products (3)

mRNA Protein Name
XM_038447083.1 XP_038303011.1 pyruvate dehydrogenase (acetyl-transferring) kinase isozyme 1, mitochondrial isoform X2
XM_038447082.1 XP_038303010.1 pyruvate dehydrogenase (acetyl-transferring) kinase isozyme 1, mitochondrial isoform X1
XM_038447084.1 XP_038303012.1 pyruvate dehydrogenase (acetyl-transferring) kinase isozyme 1, mitochondrial isoform X3

PDK1 Protein Structure

BCDHK_Adom3

BCDHK_Adom3: pfam10436 (58 - 222)

HATPase_PDK-like

HATPase_PDK-like: cd16929 (226 - 392)

  • 0
  • 100
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  • 400
  • 439 a.a.
Protein Preferred Names Protein Names

[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial

LOW QUALITY PROTEIN: pyruvate dehydrogenase (acetyl-transferring) kinase isozyme 1, mitochondrial

pyruvate dehydrogenase (acetyl-transferring) kinase isozyme 1, mitochondrial

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-N0645 Dicoumarol Inhibitor 99.89% Unkown
HY-124060 PS423 99.38% Unkown

Pre-clinical Phase

Bioactive Molecules (56)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-10514 BX795 99.84% Unkown
HY-14981 GSK2334470 Inhibitor 99.79% Unkown
HY-N0047 Polyphyllin I 99.91% Unkown
HY-11005 BX-912 99.50% Unkown
HY-15967 PS48 Activator 99.71% Unkown
HY-12492 VER-246608 Inhibitor 99.10% Unkown
HY-121744 PS10 Inhibitor 98.51% Unkown
HY-10547 OSU-03012 99.80% Unkown
HY-124379 TPCK 98.55% Unkown
HY-19564 JX06 99.78% Unkown
HY-N6769 Radicicol Inhibitor 99.96% Unkown
HY-15569 NU6102 Inhibitor 99.23% Unkown
HY-14440 MP7 Inhibitor 99.33% Unkown
HY-13842 BX517 Inhibitor 98.0% Unkown
HY-106263B Tyroserleutide hydrochloride 99.92% Unkown
HY-121629 PS210 Activator 98.30% Unkown
HY-124652 TBK1/IKKε-IN-4 Inhibitor 99.42% Unkown
HY-114645 PDK1-IN-RS2 Inhibitor 98.49% Unkown
HY-149814 PDK-IN-1 Inhibitor 99.74% Unkown
HY-157299 PDK-IN-3 Inhibitor 99.87% Unkown
HY-10515 BX-320 Inhibitor 99.4% Unkown
HY-13851 PS47 99.13% Unkown
HY-P5450A PDKtide TFA 99.07% Unkown
HY-W998345 SMART1 Inhibitor 99.87% Unkown
HY-117809 PDK1-IN-2 Inhibitor 98.90% Unkown
HY-13856 (R)-PS210 Inhibitor 98.09% Unkown
HY-151466 HIF-1α-IN-5 Inhibitor 99.95% Unkown
HY-W070306 PDK1-IN-1 Inhibitor 99.95% Unkown
HY-129426 PDK1/Akt/Flt dual pathway inhibitor Inhibitor / Unkown
HY-151465 HIF-1α-IN-4 Inhibitor 99.95% Unkown
HY-156375 PKM2 activator 6 / Unkown
HY-W837864 PDK1 allosteric modulator 1 Modulator 99.34% Unkown
HY-119134 PX-316 Inhibitor / Unkown
HY-124288 PDK1/AurA-IN-1 / Unkown
HY-12482 X-370 / Unkown
HY-135773 CRTh2 antagonist 3 / Unkown
HY-13844 PDK1-IN-3 Inhibitor / Unkown
HY-149275 PKM2/PDK1-IN-1 / Unkown
HY-156109 PDK-IN-2 / Unkown
HY-16461 Solenopsin / Unkown
HY-172142 PDK1-IN-4 Inhibitor / Unkown
HY-177913 OSU-02067 Inhibitor / Unkown
HY-179501 PDK1-IN-5 / Unkown
HY-181670 WH23 / Unkown
HY-183583 HIF-2α-IN-18 Inhibitor / Unkown
HY-N0645S Dicoumarol-d8 / Unkown
HY-N17990 Sexangularetin 3-sophoroside / Unkown
HY-P5450 PDKtide / Unkown
HY-RS10273 PDK1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10274 Pdk1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10275 Pdk1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10287 PDPK1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W074538 3-Amino-5-(2-furyl)pyrazole / Unkown
HY-117885 PF-5177624 Inhibitor / Unkown
HY-175770 mIDH1-IN-2 / Unkown
HY-RS17027 Pdpk1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens PDK1 NCBI NCBI:5163