Max - MYC associated factor X Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 60661

Summary

Enables DNA-binding transcription factor activity; identical protein binding activity; and sequence-specific DNA binding activity. Involved in several processes, including neuron apoptotic process; regulation of gene expression; and response to peptide hormone. Located in PML body; cytoplasm; and dendrite. Human ortholog(s) of this gene implicated in lung small cell carcinoma and pheochromocytoma. Orthologous to human MAX (MYC associated factor X). [provided by Alliance of Genome Resources, Apr 2022]

Max Products (2)

mRNA Protein Name
NM_001411963.1 NP_001398892.1 protein max isoform 2
NM_022210.2 NP_071546.1 protein max isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Referencias Source
enables DNA-binding transcription factor activity IMP
IMP: Inferred from mutant phenotype
17341548 RGD
enables identical protein binding IPI
IPI: Inferred from physical interaction
7791753 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
11891322 RGD
NOT enables protein-containing complex binding IDA
IDA: Inferred from direct assay
7791753 RGD
enables protein-containing complex binding IDA
IDA: Inferred from direct assay
18271930 RGD
enables protein-containing complex binding IPI
IPI: Inferred from physical interaction
17341548 RGD
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
17341548 RGD
Biological Process GO Annotation Evidence Referencias Source
involved in cellular response to peptide hormone stimulus IEP
IEP: Inferred from expression pattern
10446908 RGD
involved in cellular response to starvation IEP
IEP: Inferred from expression pattern
10446908 RGD
involved in negative regulation of gene expression IDA
IDA: Inferred from direct assay
7791753 RGD
involved in neuron apoptotic process IEP
IEP: Inferred from expression pattern
14603520 RGD
involved in protein-containing complex assembly IDA
IDA: Inferred from direct assay
18271930 RGD
involved in regulation of DNA-templated transcription IMP
IMP: Inferred from mutant phenotype
17341548 RGD
involved in response to axon injury IEP
IEP: Inferred from expression pattern
14603520 RGD
involved in response to insulin IEP
IEP: Inferred from expression pattern
10072196 RGD
involved in retina development in camera-type eye IEP
IEP: Inferred from expression pattern
14603520 RGD
Cellular Component GO Annotation Evidence Referencias Source
located in PML body IDA
IDA: Inferred from direct assay
15503302 RGD
located in dendrite IDA
IDA: Inferred from direct assay
14603520 RGD
located in nucleus IDA
IDA: Inferred from direct assay
14603520 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein max

  • myc-associated factor X

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (3)
Referencia número Nombre del producto Efecto
Pureza Phase
HY-108750 Soybean oil / Phase 4
HY-145723B MAX-40279 hemifumarate Inhibitor 99.52% Phase 2
HY-153064 MAX-10181 Inhibitor 98.56% Phase 1

Pre-clinical Phase

Bioactive Molecules (64)
Referencia número Nombre del producto
Efecto
Pureza
Rare Diseases
HY-D0218 Thioflavin T 99.40% Unkown
HY-12702 10058-F4 Inhibitor 99.90% Unkown
HY-135969 Glycol chitosan Inhibitor 61.22% Unkown
HY-124675 MYCMI-6 98.57% Unkown
HY-100996 10074-G5 Inhibitor 99.63% Unkown
HY-100669 Mycro 3 Inhibitor 98.11% Unkown
HY-W016813 trans-Aconitic acid Inhibitor 99.74% Unkown
HY-144878 VPC-70619 Inhibitor 99.93% Unkown
HY-12703 KSI-3716 Inhibitor 98.98% Unkown
HY-145603A (R)-Vanzacaftor Modulator 98.02% Unkown
HY-N5072 Desmethylglycitein Inhibitor 99.99% Unkown
HY-122683 sAJM589 Inhibitor 99.47% Unkown
HY-22445 MY05 Inhibitor 99.34% Unkown
HY-131021 Janelia Fluor® 549, Azide 99.49% Unkown
HY-145723 MAX-40279 Inhibitor 97.04% Unkown
HY-147291 VPC-70063 99.92% Unkown
HY-126979 Mycro2 Inhibitor 99.81% Unkown
HY-W591768 (E)-4-(4-(Dimethylamino)styryl)-1-methylpyridin-1-ium iodide 99.66% Unkown
HY-W007648 Methyl 3-aminopropanoate hydrochloride ≥98.0% Unkown
HY-133536 PA Janelia Fluor® 549, SE 98.2% Unkown
HY-171995 Rf470 TFA / Unkown
HY-131022 Janelia Fluor® 549 TFA 85.20% Unkown
HY-DY1049 Thioflavin T (solution) / Unkown
HY-125978 JY-3-094 Inhibitor 97.04% Unkown
HY-134975 NY2267 Inhibitor 98.53% Unkown
HY-N6919 Cauloside C Inhibitor 99.66% Unkown
HY-145723C MAX-40279 hemiadipate Inhibitor 99.26% Unkown
HY-137551 Tiafenacil Inhibitor 99.20% Unkown
HY-N6878 Cauloside D 99.69% Unkown
HY-N7273 Soyasaponin III Inducer 99.73% Unkown
HY-P10699 MAX1 95.31% Unkown
HY-145723A MAX-40279 hydrochloride Inhibitor / Unkown
HY-115796 VU0477886 Activator / Unkown
HY-115839A Detajmium L-tartrate Inhibitor / Unkown
HY-125636 Mycro1 Inhibitor / Unkown
HY-131023 Janelia Fluor® 549, Maleimide TFA / Unkown
HY-131024 Janelia Fluor® 549, Tetrazine / Unkown
HY-136784 Rhod-2 potassium / Unkown
HY-159756B KI-MS2-008 Inhibitor / Unkown
HY-160813 DHX9-IN-18 Inhibitor / Unkown
HY-165400 TODi-1 / Unkown
HY-169921 c-Myc inhibitor 15 Inhibitor / Unkown
HY-175964 MYC-MAX-IN-1 Ligand / Unkown
HY-178045 MYC-IN-4 Inhibitor / Unkown
HY-180194 SERCA2a activator 2 Activator / Unkown
HY-E71000 Lipoxidase, Glycine max (soybean) / Unkown
HY-N12273 Soyasaponin Ae / Unkown
HY-N1228 Soyacerebroside I / Unkown
HY-N18032 Glyceollin II / Unkown
HY-N18033 Glyceollin III / Unkown
HY-N20313 Black soya bean extract / Unkown
HY-N4074 6"-O-Malonylglycitin / Unkown
HY-P6299 MAX8 / Unkown
HY-RS08177 MAX Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W127781 Rhod-2 triammonium / Unkown
HY-136784A Rhod-2 sodium / Unkown
HY-169334 BDK-IN-1 / Unkown
HY-N13282 Glyceocarpin Inhibitor / Unkown
HY-N13283 Glyceollidin I / Unkown
HY-RS17397 Max Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23852 Max Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W783575 (3R)-1-Octen-3-ol / Unkown
HY-W800768 BP Fluor 350 Azide Plus / Unkown
HY-W800769 BP Fluor 532 azide plus / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Max NCBI NCBI:4149