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Cat. No.: HY-189350

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HDAC6 ligand-11

HDAC6 ligand-11 is a HDAC6 ligand. HDAC6 ligand-11 can be used as a target protein ligand for the synthesis of PROTAC HDAC6 degrader-13 (HY-189306). HDAC6 ligand-11 can be used for research on acute myeloid leukemia.

For research use only. We do not sell to patients.

Formula: C₁₇H₁₆ClN₃O₄
Molecular Weight:361.78

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

HDAC6 ligand-11 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

IC₅₀ & Target

^[1]

HDAC6

All HDAC Isoforms :

In Vitro

HDAC6 ligand-11 can serve as a target protein ligand for the synthesis of PROTAC HDAC6 degrader-13 (HY-189306)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .

Chemical Information

Molecular Weight 361.78
Formula C₁₇H₁₆ClN₃O₄
SMILES

O=C(N(CC(N)=O)CC1=CC=C(C(NO)=O)C=C1)C2=CC=CC=C2Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Tsymliakov M, et al. Rapid Two-Step Multicomponent Synthesis and Structure-degradation Relationships of Selective HDAC6 PROTAC Degraders. Journal of medicinal chemistry. 2026 Sep 10;69(17):21018-21043.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References

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HDAC6 ligand-11

All HDAC Isoforms

Biological Activity

Description

IC50 & Target

In Vitro

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

HDAC6 ligand-11 Related Classifications

HY-189350 Related Classifications

Bioz

Keywords

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