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Cat. No.: HY-187005

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HDAC8 ligand 2

HDAC8 ligand 2 is a HDAC8 ligand that can be used for the synthesis of PROTACs, such as SZUH280 (HY-152147).

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Formule: C₁₆H₁₄N₂O₃
Masse moléculaire:282.29

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Please store the product under the recommended conditions in the Certificate of Analysis.

HDAC8 ligand 2 Chemical Structure

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références
Calculators
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Description

HDAC8 ligand 2 is a HDAC8 ligand that can be used for the synthesis of PROTACs, such as SZUH280 (HY-152147)^[1].

IC₅₀ & Target^[1]

HDAC8

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Chemical Information

Masse moléculaire 282.29
Formule C₁₆H₁₄N₂O₃
SMILES

O=C(NO)C1=CC=C2C(N(CC3=CC=C(O)C=C3)C=C2)=C1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Huang J, et al. Structure-Based Discovery of Selective Histone Deacetylase 8 Degraders with Potent Anticancer Activity. J Med Chem. 2022 Dec 14. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références

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HDAC8 ligand 2

Voir tous les produits spécifiques à Isoform HDAC

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

HDAC8 ligand 2 Related Classifications

HY-187005 Related Classifications