NL-103
NL-103 is an inhibitor of histone deacetylases (HDACs) and Hedgehog, with the IC50 values of 21.3 nM, 57 nM, 74 nM, and 680 nM for HDAC1, HDAC2, HDAC3, and HDAC6, respectively. NL-103 can downregulate the expression of Gli2. NL-103 can be used in anti-cancer research.
For research use only. We do not sell to patients.
- CAS No.: 1788896-33-2
- Formula: C26H27Cl2N5O4
- Molecular Weight:544.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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HDAC1 21.3 nM (IC50) |
HDAC2 57 nM (IC50) |
HDAC3 74 nM (IC50) |
HDAC6 680 nM (IC50) |
Chemical Information
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CAS No. 1788896-33-2
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Molecular Weight 544.43
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Formula C26H27Cl2N5O4
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SMILES
O=C(C1=CN=C(NCCCCCCC(NO)=O)C=C1)NC2=CC=C(C(NC(C3=CC(Cl)=CC=C3)=O)=C2)Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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