ZSQ836
ZSQ836 is an orally active dual covalent inhibitor of CDK12/CDK13, with an EC50 value of 32 nM against CDK12. ZSQ836 can induce apoptosis and exhibit anticancer activity in vivo. ZSQ836 can be used in the study of ovarian cancer.
For research use only. We do not sell to patients.
- CAS No.: 2634811-35-9
- Formula: C27H28AsClN6OS2
- Molecular Weight:627.06
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
EC50: 32 nM (CDK12)[1].
Chemical Information
-
CAS No. 2634811-35-9
-
Molecular Weight 627.06
-
Formula C27H28AsClN6OS2
-
SMILES
ClC1=CN=C(N[C@H]2CN(CCC2)CC(NC3=CC=C([As]4SCCS4)C=C3)=O)N=C1C5=CNC6=CC=CC=C56
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)