JE-133
JE-133 is an optically active isochromane-2H-chromene conjugate. JE-133 exhibits antioxidant and anti-inflammatory activities. JE-133 is a neuroprotective agent that effectively inhibits neuronal oxidative damage associated with PI3K/Akt and MAPK signaling pathways. JE-133 can also inhibit lipopolysaccharide (LPS) (HY-D1056)-induced neuroinflammation by regulating JAK/STAT and Nrf2 signaling pathways.
For research use only. We do not sell to patients.
- CAS No.: 2579171-69-8
- Formula: C23H24O7
- Molecular Weight:412.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 2579171-69-8
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Molecular Weight 412.43
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Formula C23H24O7
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SMILES
CCOC([C@@H]1C([C@H]2C3=CC(O)=C(O)C=C3C[C@H](O2)C)=CC4=CC(OC)=CC=C4O1)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Tao L, et al. JE-133 Suppresses LPS-Induced Neuroinflammation Associated with the Regulation of JAK/STAT and Nrf2 Signaling Pathways[J]. ACS Chemical Neuroscience, 2024. [Content Brief]
[2]. Tao L, et al. An optically active isochroman-2 H-chromene conjugate potently suppresses neuronal oxidative injuries associated with the PI3K/Akt and MAPK signaling pathways[J]. Acta Pharmacologica Sinica, 2021, 42(1): 36-44. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
JE-133 Related Classifications
HY-163151 Related Classifications
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