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キサントトキシン

(別名: Methoxsalen; 8-Methoxypsoralen; Xanthotoxin; 8-MOP)
17 Cited Publications
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Based on 17 publication(s) in Google Scholar

Methoxsalen (8-Methoxypsoralen) is a furanocoumarin compound used in psoralen, used in studies of psoriasis, eczema, vitiligo and some sun-exposed cutaneous lymphomas, and is a P450 inhibitor.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
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  • 純度: 99.97%
  • CAS 番号: 298-81-7
  • 分子式: C12H8O4
  • 分子量:216.19
  • 保管条件:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 2 years , -20°C, 1 year
  • Methoxsalen Chemical Structure
    Methoxsalen 構造式
  • Experimental Validation Results for Methoxsalen
  • Experimental Validation Results for Methoxsalen
  • Experimental Validation Results for Methoxsalen
  • Experimental Validation Results for Methoxsalen
  • Experimental Validation Results for Methoxsalen
CAS 番号: 298-81-7
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MedChemExpress（MCE）の使用を引用している文献 Methoxsalen

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  • Methoxsalen Chemical Structure
    Methoxsalen Chemical Structure
    1/16
  • 1/16

    Methoxsalen purchased from MedChemExpress. Usage Cited in: Insect Biochem Mol Biol. 2022 Jul:146:103796. [Abstract]

    Customer Validation
     Qualitative enzyme activities to Methoxsalen (xanthotoxin) with six recombinant mutants.

  • 1/16

    Methoxsalen purchased from MedChemExpress. Usage Cited in: Clin Chem. 2019 Dec;65(12):1522-1531. [Abstract]

    Customer Validation
     Top-ranked ingredients associated with false positives on the amphetamines and buprenorphine screens.

  • 1/16

    Methoxsalen purchased from MedChemExpress. Usage Cited in: Nat Commun. 2018 Nov 16;9(1):4820. [Abstract]

    Customer Validation
     Compared with the SCD strain, LC50 values were significantly decreased to Methoxsalen (xanthotoxin, 4.1-fold) and 2-tridecanone (1.4-fold) in the knockout SCD-d6AE strain.

  • 1/16

    Methoxsalen purchased from MedChemExpress. Usage Cited in: Nat Commun. 2018 Nov 16;9(1):4820. [Abstract]

    Customer Validation
     Metabolism of Methoxsalen (xanthotoxin), 2-tridecanone, and indoxacarb by recombinant P450s. CYP6AE subfamily enzymes were from H. armigera and CYP6B1 from Papilio polyxenes. Error bars represent mean values ± SEM (n = 4). Asterisk indicates that no significant metabolism was detected (limits of detection were 0.081, 0.033, and 0.016 pmol/min/pmol P450 for Methoxsalen (xanthotoxin), 2-tridecanone, and indoxacarb, respectively).

  • 1/16

    Methoxsalen purchased from MedChemExpress. Usage Cited in: Nat Commun. 2018 Nov 16;9(1):4820. [Abstract]

    Customer Validation
     The results showed that the CYP6AE19 and CYP6AE20 transcripts (>1000-fold induction in midgut and >100-fold induction in fat body) are very strongly induced by Methoxsalen (xanthotoxin). Furthermore, CYP6AE14 transcripts are induced in midgut (40-fold) after dietary exposure to gossypol.

  • Methoxsalen