DC_C66
DC_C66 is a cell-permeable, selective coactivator associated arginine methyltransferase 1 (CARM1) inhibitor with an IC50 of 1.8 μM. DC_C66 has a good selectivity for CARM1 against PRMT1 (IC50=21 μM), PRMT6 (IC50= 47μM), and PRMT5.
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- CAS 番号: 108181-00-6
- 分子式: C28H22NO2+
- 分子量:404.48
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Histone Methyltransferase アイソフォーム固有の製品をすべて表示
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生物活性
IC50: 1.8 μM (CARM1)[1]
DC_C66 (6.25-100 μM; 24-72 hours) exhibits antiproliferation activity in several CARM1-associated cancer cell lines[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:HELA, K562, MCF7 cells
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Concentration:6.25, 12.5, 25, 50, 100 μM
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Incubation Time:24, 48, 72 hours
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Result:Inhibits proliferation of cancer cells in a time-dependent and dose-dependent manner in HELA, K562, and MCF7 cells.
化学情報
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CAS 番号 108181-00-6
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分子量 404.48
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分子式 C28H22NO2+
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SMILES
O=C(OCC)C1=[N+]2C(C(C=CC=C3)=C3CC2)=CC4=C1C(C=CC=C5)=C5C6=C4C=CC=C6
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
DC_C66 関連分類
HY-100855 関連分類
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