Nexopamil
Based on 1 Customer Validation
Nexopamil is a calcium antagonist of Ca2+ channel, 5HT2, 5HT1A, 5HT1C and dopamine D2 receptors. Nexopamil exhibits vasodilatory, cardioprotective, and platelet aggregation inhibiting effects. Nexopamil can be used for researches of stable or unstable angina and possibly of peripheral arterial occlusive disease.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.57%
- CAS 番号: 136033-49-3
- 分子式: C24H40N2O3
- 分子量:404.59
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- プロトコル
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Calcium Channel アイソフォーム固有の製品をすべて表示
More5-HT Receptor アイソフォーム固有の製品をすべて表示
MoreDopamine Receptor アイソフォーム固有の製品をすべて表示
More
生物活性
製品説明
IC50 & Target
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5-HT1A Receptor |
5-HT1C Receptor |
化学情報
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CAS 番号 136033-49-3
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性状 Solid
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分子量 404.59
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分子式 C24H40N2O3
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Color White to off-white
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SMILES
CCCCCCN(C)CCC[C@@](C#N)(C1=CC(OC)=C(OC)C(OC)=C1)C(C)C
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : 100 mg/mL (247.16 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
プロトコル
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Ca2+ Staining Technique
Ca2+ staining is an experimental technique that utilizes specific fluorescent probes (such as Fluo-4 AM, Fura-2, etc.) to qualitatively or quantitatively detect dynamic changes in intracellular Ca2+ concentrations; this is achieved by monitoring the changes in fluorescent signals generated when these probes bind to free intracellular calcium ions. The underlying principle relies primarily on the presence of chelating groups within the probe's molecular structure that possess high affinity for calcium ions.
純度とドキュメンテーション
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データシート (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4716 mL | 12.3582 mL | 24.7164 mL | 61.7909 mL |
| 5 mM | 0.4943 mL | 2.4716 mL | 4.9433 mL | 12.3582 mL | |
| 10 mM | 0.2472 mL | 1.2358 mL | 2.4716 mL | 6.1791 mL | |
| 15 mM | 0.1648 mL | 0.8239 mL | 1.6478 mL | 4.1194 mL | |
| 20 mM | 0.1236 mL | 0.6179 mL | 1.2358 mL | 3.0895 mL | |
| 25 mM | 0.0989 mL | 0.4943 mL | 0.9887 mL | 2.4716 mL | |
| 30 mM | 0.0824 mL | 0.4119 mL | 0.8239 mL | 2.0597 mL | |
| 40 mM | 0.0618 mL | 0.3090 mL | 0.6179 mL | 1.5448 mL | |
| 50 mM | 0.0494 mL | 0.2472 mL | 0.4943 mL | 1.2358 mL | |
| 60 mM | 0.0412 mL | 0.2060 mL | 0.4119 mL | 1.0298 mL | |
| 80 mM | 0.0309 mL | 0.1545 mL | 0.3090 mL | 0.7724 mL | |
| 100 mM | 0.0247 mL | 0.1236 mL | 0.2472 mL | 0.6179 mL |
Nexopamil 関連分類
HY-106904 関連分類
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