TRP-601
Based on 1 publication(s) in Google Scholar
TRP-601 is a caspase inhibitor. TRP-601 reversed the increased expression of active caspase-2, the activation of endogenous apoptotic pathway and the up-regulation of key protein triggered by hyperoxia.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1094569-02-4
- 分子式: C40H48F2N6O11
- 分子量:826.84
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
MedChemExpress（MCE）の使用を引用している文献 TRP-601
MoreCaspase アイソフォーム固有の製品をすべて表示
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生物活性
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Caspase-2 |
Caspase 3 |
Bcl-2 |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Wistar rats [1]
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Dosage:1 mg/kg
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Administration:Intraperitoneal injection (i.p.)
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Result:Ameliorated the increase of caspase-3 activity and reduced protein expression of processed caspase-2 and enzymatic activity. Significantly reduced neuronal cell death and did not influence levels of physiological apoptosis. Decreased Apaf-1 protein expression to control levels. Increased mRNA expression of Bcl-2.
化学情報
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CAS 番号 1094569-02-4
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分子量 826.84
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分子式 C40H48F2N6O11
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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Phytomedicine
The protective mechanism of Hydroxysafflor yellow A for the treatment of stroke - heart - syndrome via activating the ZBP1-NLRP3 signaling pathway. [Abstract]2025 Sep:145:157011. PMID: 40602292
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
TRP-601 関連分類
HY-P2012 関連分類
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