CDK4-IN-8
CDK4-IN-8 is a selective CDK4 inhibitor with no activity against CDK6, and it inhibits the proliferation of breast cancer cells. CDK4-IN-8 can be used in breast cancer-related research.
For research use only. We do not sell to patients.
- CAS No.: 2764984-10-1
- Formula: C27H31FN6OS
- Molecular Weight:506.64
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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CDK4 |
CDK4-IN-8 (example 98) exhibits potent inhibitory activity against CDK4_D1 kinase, shows moderate antiproliferative activity against MCF7 adenocarcinoma cells, and has no obvious inhibitory activity against CDK6_D1 kinase[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2764984-10-1
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Molecular Weight 506.64
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Formula C27H31FN6OS
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SMILES
O=C1C2=C(SC(C=3N=C(N=CC3F)NC4=NC=C(C=C4)C5CCN(C)CC5)=C2C)C(=CN1C)C(C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)