CDK5-IN-3
Based on 1 Customer Validation
CDK5-IN-3 (compound 11) is a potent CDK5 inhibitor, with IC50s of 0.6 nM and 18 nM for CDK5/p25 and CDK2/CycA, respectively. CDK5-IN-3 can be used for the research of autosomal dominant polycystic kidney disease (ADPKD).
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 98.99%
- CAS No.: 2639542-32-6
- 화학식: C22H26N4O
- 분자량:362.47
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
Biological Activity
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Cdk5/p25 0.6 nM (IC50) |
CDK2/CycA 18 nM (IC50) |
Chemical Information
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CAS No. 2639542-32-6
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Appearance Solid
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분자량 362.47
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화학식 C22H26N4O
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Color Light yellow to yellow
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SMILES
C[C@@](C1=CC=C2C(C=C(NC3=CC=CC=C3)N=C2)=N1)(O)C4CCN(C)CC4
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
DMSO : 10 mg/mL (27.59 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (274 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.7588 mL | 13.7942 mL | 27.5885 mL | 68.9712 mL |
| 5 mM | 0.5518 mL | 2.7588 mL | 5.5177 mL | 13.7942 mL | |
| 10 mM | 0.2759 mL | 1.3794 mL | 2.7588 mL | 6.8971 mL | |
| 15 mM | 0.1839 mL | 0.9196 mL | 1.8392 mL | 4.5981 mL | |
| 20 mM | 0.1379 mL | 0.6897 mL | 1.3794 mL | 3.4486 mL | |
| 25 mM | 0.1104 mL | 0.5518 mL | 1.1035 mL | 2.7588 mL |
CDK5-IN-3 Related Classifications
HY-145694 Related Classifications
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