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Cat. No.: HY-109855

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CP-67015

CP-67015, a quinolone antibiotic, is a potent topoisomerase II inhibitor. CP-67015 is a positive direct-acting mutagen in mammalian cells with both gene and chromosomal level effects.

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CAS No.: 100325-51-7
화학식: C₁₇H₁₂F₂N₂O₃
분자량:330.29

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

CP-67015 Chemical Structure

CAS No.: 100325-51-7

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
- In Vivo
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

CP-67015, a quinolone antibiotic, is a potent topoisomerase II inhibitor. CP-67015 is a positive direct-acting mutagen in mammalian cells with both gene and chromosomal level effects^[1].

IC₅₀ & Target^[1]

Quinolone

Topoisomerase II

All Topoisomerase Isoforms :

All Antibiotic Isoforms :

In Vitro

CP-67015 (10-100 μg/mL; 12-36 h) produces a drastic increase in chromosome damage in human lymphocytes and in CHO cells^[1].
CP-67015 inhibits supercoiling activity of prokaryotic DNA gyrase, with 100% inhibition at the concentration of 4.0 μg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

CP-67015 (a single dose 1000 mg/kg or 500 mg/kg/day for 5 days; i.p.) induces chromosome damage in male CD-1 mice in mouse bone marrow cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 100325-51-7
분자량 330.29
화학식 C₁₇H₁₂F₂N₂O₃
SMILES

O=C(C1=CN(CC)C2=C(C=C(F)C(C3=CC=NC=C3)=C2F)C1=O)O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Holden HE, et, al. Genetic profile of a nalidixic acid analog: a model for the mechanism of sister chromatid exchange induction. Environ Mol Mutagen. 1989;13(3):238-52. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

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Concentration _(final) Concentration _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
- In Vivo
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
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상품명:
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CP-67015

All Topoisomerase Isoforms

All Antibiotic Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

CP-67015 Related Classifications

HY-109855 Related Classifications