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HL23

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HL23 is a histone deacetylase (HDAC) inhibitor with activity against hepatocellular carcinoma (HCC). HL23 enhances acetylation of the TXNIP promoter and upregulates TXNIP expression, thereby mediating potassium channel activity and triggering TXNIP-dependent potassium deprivation. HL23 inhibits HCC progression and metastasis and has a synergistic effect with Sorafenib (HY-10201) and is more potent than Sorafenib+Vorinostat (HY-10221).

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  • Purity: 99.64%
  • CAS No.: 1448355-15-4
  • 화학식: C44H44N2O7
  • 분자량:712.83
  • 보관:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 6 months , -20°C, 1 month
  • HL23 Chemical Structure
    HL23 Chemical Structure
CAS No.: 1448355-15-4
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    HL23 Chemical Structure
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