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Cat. No.: HY-161854

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LASSBio-1911

LASSBio-1911 is a potent inhibitor of HDAC6. LASSBio-1911 shows antitumor in hepatocellular carcinoma (HCC) cells with minimal on normal cells.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

화학식: C₁₇H₁₈N₄O₃
분자량:326.35

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

LASSBio-1911 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

LASSBio-1911 is a potent inhibitor of HDAC6. LASSBio-1911 shows antitumor in hepatocellular carcinoma (HCC) cells with minimal on normal cells^[1].

IC₅₀ & Target

HDAC6

All HDAC Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
HepG2	IC₅₀	9.48 μM Compound: 3c	Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by MTS assay Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by MTS assay	[PMID: 26705137]
HT-144	IC₅₀	21.18 μM Compound: 3c	Antiproliferative activity against human HT144 cells assessed as reduction in cell viability after 48 hrs by MTS assay Antiproliferative activity against human HT144 cells assessed as reduction in cell viability after 48 hrs by MTS assay	[PMID: 26705137]

Chemical Information

분자량 326.35
화학식 C₁₇H₁₈N₄O₃
SMILES

O=C(N/N=C/C1=CC=C(C(NO)=O)C=C1)C2=CC=C(N(C)C)C=C2
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Guilherme Álvaro Ferreira-Silva, et al. Selective inhibition of HDAC6 by N-acylhydrazone derivative reduces the proliferation and induces senescence in carcinoma hepatocellular cells. Toxicol In Vitro. 2024 Aug:99:105884. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
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Purity:
수량:

LASSBio-1911

All HDAC Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

LASSBio-1911 Related Classifications

HY-161854 Related Classifications