Leuxinostat
Leuxinostat is an inhibitor for HDAC with IC50 of 30 nM for hHDAC6. Leuxinostat inhibits the proliferation of cells THP1, K562, U937 and MEK1, induces apoptosis in leukemia cells NB4 and MOLT-4. Leuxinostat inhibits the expansion of hematopoietic stem cells and exhibits antileukemic activity in zebrafish models.
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- 화학식: C18H20N4O4
- 분자량:356.38
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
|
hHDAC6 0.03 μM (IC50) |
hHDAC1 1.203 μM (IC50) |
hHDAC8 2.446 μM (IC50) |
hHDAC3 2.858 μM (IC50) |
hHDAC10 4.811 μM (IC50) |
hHDAC11 5.57 μM (IC50) |
Chemical Information
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분자량 356.38
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화학식 C18H20N4O4
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SMILES
O=C(NO)C(C=C1)=CC=C1CN2CCN(C3=CC=C([N+]([O-])=O)C=C3)CC2
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Leuxinostat Related Classifications
HY-162658 Related Classifications
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