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Cat. No.: HY-100832A

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UNC3866 TFA

3 Cited Publications

고객리뷰

Based on 3 publication(s) in Google Scholar

UNC3866 TFA is a potent antagonist of the CBX7-H3 interaction as determined by AlphaScreen (IC₅₀=66±1.2 nM) and is more than 100-fold selective for CBX7 over the other nine members of this methyl-lysine (Kme) reader panel.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 1872382-48-3
화학식: C₄₅H₆₇F₃N₆O₁₀
분자량:909.04

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

UNC3866 TFA Chemical Structure

CAS No.: 1872382-48-3

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

All Histone Methyltransferase Isoforms :

Chemical Information

CAS No. 1872382-48-3
분자량 909.04
화학식 C₄₅H₆₇F₃N₆O₁₀
Sequence

{Phe}-Ala-Leu-{Lys}-{Ser}
Sequence Shortening

{Phe}-AL-{Lys}-{Ser}
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (3)

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Journal Impact Factor

Nat Commun

Human iPSC-based Modeling of Pulmonary Fibrosis Reveals p300/CBP Inhibition Suppresses Alveolar Transitional Cell State. [Abstract]

2026 Feb 12;17(1):1214. PMID: 41680175
Acta Pharmacol Sin

P300/CBP inhibition sensitizes mantle cell lymphoma to PI3Kδ inhibitor idelalisib. [Abstract]

2022 Feb;43(2):457-469. PMID: 33850273
bioRxiv

2021 May 26.

순도&문서

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (259 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Stuckey JI, et al. A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1. Nat Chem Biol. 2016 Mar;12(3):180-7. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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UNC3866 TFA

3 Cited Publications

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Biological Activity
- 제품 설명
Chemical Information
Publications (3)
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References

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UNC3866 TFA

Publications Citing Use of MedChemExpress (MCE) UNC3866 TFA

All Histone Methyltransferase Isoforms

Biological Activity

Chemical Information

Publications (3)

순도&문서

References

Calculators

Help & FAQs

UNC3866 TFA Related Classifications

HY-100832A Related Classifications