Mazapertine
Based on 1 Customer Validation
Mazapertine is an orally active antipsychotic agent. M azapertine antagonizes to dopamine D2/3/4 receptors (Ki values < 3 nM) and also strongly binds to serotonin 5-HT1A receptor (Ki =1.7 nM) and α1-adrenergic receptor (Ki = 1.3 nM). Mazapertine can be used for the research of neurological disease.
For research use only. We do not sell to patients.
- Purity: 99.37%
- CAS No.: 134208-17-6
- Formula: C26H35N3O2
- Molecular Weight:421.58
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Storage:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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All Dopamine Receptor Isoforms
MoreAll 5-HT Receptor Isoforms
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Biological Activity
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D2 Receptor <3 nM (Ki) |
D3 Receptor <3 nM (Ki) |
D4 Receptor <3 nM (Ki) |
α1-adrenergic receptor 1.3 nM (Ki) |
5-HT1A Receptor 1.7 nM (Ki) |
Chemical Information
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CAS No. 134208-17-6
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Appearance Oil
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Molecular Weight 421.58
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Formula C26H35N3O2
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Color Yellow to brown
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SMILES
CC(C)OC1=C(N2CCN(CC3=CC(C(N4CCCCC4)=O)=CC=C3)CC2)C=CC=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
DMSO : 100 mg/mL (237.20 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3720 mL | 11.8601 mL | 23.7203 mL | 59.3007 mL |
| 5 mM | 0.4744 mL | 2.3720 mL | 4.7441 mL | 11.8601 mL | |
| 10 mM | 0.2372 mL | 1.1860 mL | 2.3720 mL | 5.9301 mL | |
| 15 mM | 0.1581 mL | 0.7907 mL | 1.5814 mL | 3.9534 mL | |
| 20 mM | 0.1186 mL | 0.5930 mL | 1.1860 mL | 2.9650 mL | |
| 25 mM | 0.0949 mL | 0.4744 mL | 0.9488 mL | 2.3720 mL | |
| 30 mM | 0.0791 mL | 0.3953 mL | 0.7907 mL | 1.9767 mL | |
| 40 mM | 0.0593 mL | 0.2965 mL | 0.5930 mL | 1.4825 mL | |
| 50 mM | 0.0474 mL | 0.2372 mL | 0.4744 mL | 1.1860 mL | |
| 60 mM | 0.0395 mL | 0.1977 mL | 0.3953 mL | 0.9883 mL | |
| 80 mM | 0.0297 mL | 0.1483 mL | 0.2965 mL | 0.7413 mL | |
| 100 mM | 0.0237 mL | 0.1186 mL | 0.2372 mL | 0.5930 mL |
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