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Cat. No.: HY-107364R

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MTX-211 (Standard)

Name: MTX-211 (Standard)
Brand: MedChemExpress
SKU: HY-107364R
Price: 180.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: Mol 211 (Standard))

MTX-211 (Standard) (Mol 211 (Standard)) is the analytical standard of MTX-211 (HY-107364). This product is intended for research and analytical applications. MTX-211 (Mol 211) is a dual inhibitor of EGFR and PI3K with IC₅₀ values of ＜100 nM. MTX-211 can be used for the research of cancer and other diseases.

For research use only. We do not sell to patients.

CAS No.: 1952236-05-3
Formula: C₂₀H₁₄Cl₂FN₅O₂S
Molecular Weight:478.33

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

MTX-211 (Standard) Chemical Structure

CAS No.: 1952236-05-3

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Top Publications Citing

Use of MCE Products

Antibody-Drug Conjugates

One-stop solution for XDC (ADC/PDC/RDC/ApDC/FDC/ISAC/VDC/SMDC)

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Protocols (1)
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

IC₅₀ & Target

IC50: ＜100 nM (EGFR/PI3K)^[1]

All EGFR Isoforms :

All PI3K Isoforms :

Chemical Information

CAS No. 1952236-05-3
Molecular Weight 478.33
Formula C₂₀H₁₄Cl₂FN₅O₂S
SMILES

CS(NC1=CC(C2=CC(C(NC3=CC(Cl)=C(F)C=C3)=NC=N4)=C4C=C2)=CN=C1Cl)(=O)=O
Synonyms

Mol 211 (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocols

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Small molecule inhibitors of egfr and pi3k. WO 2016100347 A2

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Protocols
Purity & Documentation
References

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MTX-211 (Standard)

All EGFR Isoforms

All PI3K Isoforms

Biological Activity

Description

IC50 & Target

Chemical Information

Protocols

Purity & Documentation

References

Calculators

Help & FAQs

MTX-211 (Standard) Related Classifications

HY-107364R Related Classifications

Bioz

Keywords

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