MS910
MS910 is an efficient and selective MEK1/2 PROTAC degrader. MS910 exhibits effective MEK1/2 degradation ability and anti proliferative activity in various cancer cells, such as HT-29 (MEK1 DC50 = 118 nM, MEK2 DC50 = 55 nM) and SK-MEL-28 (MEK1 DC50 = 94 nM, MEK2 DC50 = 38 nM) cells. MS910 is commonly used in cancer research. (Pink: MEK1/2 Ligand (HY-10254); Blue: CRBN Ligand (HY-W087383); Black: Linker (HY-W022240))
(Pink: MEK1 and MEK2 ligand (HY-10254); Blue: Cereblon ligand (HY-W087383); Black: linker (HY-W022240)).
For research use only. We do not sell to patients.
- CAS No.: 2756323-28-9
- Formula: C41H48F3IN6O11
- Molecular Weight:984.75
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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MEK1 |
MEK2 |
Cereblon |
Chemical Information
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CAS No. 2756323-28-9
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Molecular Weight 984.75
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Formula C41H48F3IN6O11
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SMILES
O=C(C1=CC=C(C(F)=C1NC2=CC=C(C=C2F)I)F)NOCCCNCCOCCOCCOCCOCCOCCNC3=CC=C4C(N(C5C(NC(CC5)=O)=O)C(C4=C3)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MS910 Related Classifications
HY-170982 Related Classifications
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