PPA-037
PPA-037 is an orally active, highly potent and selective inhibitor of cyclin-dependent kinase 12 (CDK12). PPA-037 induces the degradation of cyclin K (Cyclin K), enhancing antiproliferative effects on tumor cells. PPA-037 is promising for research of cancers.
For research use only. We do not sell to patients.
- CAS No.: 2883700-83-0
- Formula: C25H27N7
- Molecular Weight:425.53
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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CDK12/Cyclin K |
Chemical Information
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CAS No. 2883700-83-0
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Molecular Weight 425.53
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Formula C25H27N7
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SMILES
C1(CNC2=CC(N[C@H]3CCNC3)=NC4=C(C5CC5)C=NN24)=CC=C(C6=CC=CC=N6)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)