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Cat. No.: HY-124341

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ND-378

ND-378 is a potent and selective inhibitor of matrix metalloproteinases (MMP-2) with a K_i value of 230 nM. ND-378 can be used to study spinal cord injury (SCI).

For research use only. We do not sell to patients.

CAS No.: 1807453-72-0
Formula: C₁₈H₁₉NO₄S₂
Molecular Weight:377.48

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

ND-378 Chemical Structure

CAS No.: 1807453-72-0

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

ND-378 is a potent and selective inhibitor of matrix metalloproteinases (MMP-2) with a K_i value of 230 nM. ND-378 can be used to study spinal cord injury (SCI)^[1].

All MMP Isoforms :

Chemical Information

CAS No. 1807453-72-0
Molecular Weight 377.48
Formula C₁₈H₁₉NO₄S₂
SMILES

O=C(C)NCC1=CC=C(C=C1)OC2=CC=C(S(=O)(CC3SC3)=O)C=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Gao M, et al. Selective Inhibition of MMP-2 Does Not Alter Neurological Recovery after Spinal Cord Injury. ACS Chem Neurosci. 2016 Nov 16;7(11):1482-1487. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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