Nexopamil
Based on 1 Customer Validation
Nexopamil is a calcium antagonist of Ca2+ channel, 5HT2, 5HT1A, 5HT1C and dopamine D2 receptors. Nexopamil exhibits vasodilatory, cardioprotective, and platelet aggregation inhibiting effects. Nexopamil can be used for researches of stable or unstable angina and possibly of peripheral arterial occlusive disease.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté : 99.57%
- CAS No.: 136033-49-3
- Formule: C24H40N2O3
- Masse moléculaire:404.59
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
Voir tous les produits spécifiques à Isoform Calcium Channel
MoreVoir tous les produits spécifiques à Isoform 5-HT Receptor
MoreVoir tous les produits spécifiques à Isoform Dopamine Receptor
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Activité biologique
Description
IC50 & Target
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5-HT1A Receptor |
5-HT1C Receptor |
Chemical Information
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CAS No. 136033-49-3
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Appearance Solid
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Masse moléculaire 404.59
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Formule C24H40N2O3
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Color White to off-white
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SMILES
CCCCCCN(C)CCC[C@@](C#N)(C1=CC(OC)=C(OC)C(OC)=C1)C(C)C
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
In Vitro:
DMSO : 100 mg/mL (247.16 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Protocole
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Ca2+ Staining Technique
Ca2+ staining is an experimental technique that utilizes specific fluorescent probes (such as Fluo-4 AM, Fura-2, etc.) to qualitatively or quantitatively detect dynamic changes in intracellular Ca2+ concentrations; this is achieved by monitoring the changes in fluorescent signals generated when these probes bind to free intracellular calcium ions. The underlying principle relies primarily on the presence of chelating groups within the probe's molecular structure that possess high affinity for calcium ions.
Pureté et documentation
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Fiche technique (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 2.4716 mL | 12.3582 mL | 24.7164 mL | 61.7909 mL |
| 5 mM | 0.4943 mL | 2.4716 mL | 4.9433 mL | 12.3582 mL | |
| 10 mM | 0.2472 mL | 1.2358 mL | 2.4716 mL | 6.1791 mL | |
| 15 mM | 0.1648 mL | 0.8239 mL | 1.6478 mL | 4.1194 mL | |
| 20 mM | 0.1236 mL | 0.6179 mL | 1.2358 mL | 3.0895 mL | |
| 25 mM | 0.0989 mL | 0.4943 mL | 0.9887 mL | 2.4716 mL | |
| 30 mM | 0.0824 mL | 0.4119 mL | 0.8239 mL | 2.0597 mL | |
| 40 mM | 0.0618 mL | 0.3090 mL | 0.6179 mL | 1.5448 mL | |
| 50 mM | 0.0494 mL | 0.2472 mL | 0.4943 mL | 1.2358 mL | |
| 60 mM | 0.0412 mL | 0.2060 mL | 0.4119 mL | 1.0298 mL | |
| 80 mM | 0.0309 mL | 0.1545 mL | 0.3090 mL | 0.7724 mL | |
| 100 mM | 0.0247 mL | 0.1236 mL | 0.2472 mL | 0.6179 mL |
Nexopamil Related Classifications
HY-106904 Related Classifications
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