PB94
Based on 1 Customer Validation
PB94 is a selective HDAC11 inhibitor (IC50=108 nM). PB94 can be radiolabeled as [11C]-PB94 for use in positron emission tomography (PET), as well as brain uptake and metabolic properties in administered live animals. PB94 improves neuropathic pain in mice and could be used to study neurological indications.
For research use only. We do not sell to patients.
- Purity: 98.02%
- CAS No.: 3032970-74-1
- Formula: C29H33N3O4
- Molecular Weight:487.59
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
IC50: 108 nM (HDAC11)[1]
Chemical Information
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CAS No. 3032970-74-1
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Appearance Solid
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Molecular Weight 487.59
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Formula C29H33N3O4
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Color White to off-white
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SMILES
O=C(C1=CC=C2C(C=CN2CC(C=C3)=CC(OC)=C3C(NO)=O)=C1)NCC4(C[C@@H](C5)C6)C[C@@H]6C[C@@H]5C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 87.5 mg/mL (179.45 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0509 mL | 10.2545 mL | 20.5090 mL | 51.2726 mL |
| 5 mM | 0.4102 mL | 2.0509 mL | 4.1018 mL | 10.2545 mL | |
| 10 mM | 0.2051 mL | 1.0255 mL | 2.0509 mL | 5.1273 mL | |
| 15 mM | 0.1367 mL | 0.6836 mL | 1.3673 mL | 3.4182 mL | |
| 20 mM | 0.1025 mL | 0.5127 mL | 1.0255 mL | 2.5636 mL | |
| 25 mM | 0.0820 mL | 0.4102 mL | 0.8204 mL | 2.0509 mL | |
| 30 mM | 0.0684 mL | 0.3418 mL | 0.6836 mL | 1.7091 mL | |
| 40 mM | 0.0513 mL | 0.2564 mL | 0.5127 mL | 1.2818 mL | |
| 50 mM | 0.0410 mL | 0.2051 mL | 0.4102 mL | 1.0255 mL | |
| 60 mM | 0.0342 mL | 0.1709 mL | 0.3418 mL | 0.8545 mL | |
| 80 mM | 0.0256 mL | 0.1282 mL | 0.2564 mL | 0.6409 mL | |
| 100 mM | 0.0205 mL | 0.1025 mL | 0.2051 mL | 0.5127 mL |
PB94 Related Classifications
HY-149766 Related Classifications
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