2. Cell Cycle/DNA Damage Epigenetics
  3. HDAC
  4. OKI-006

OKI-006 is an orally active histone deacetylase (HDAC) inhibitor. OKI-006 is the active metabolite of OKI-005 (HY-185584) and OKI-179 (HY-156602). OKI-006 can be used for the research of cancers such as breast cancer and colorectal cancer.

For research use only. We do not sell to patients.

OKI-006

OKI-006 Chemical Structure

CAS No. : 1315334-23-6

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OKI-006 Related Antibodies

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HDAC HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HDAC7 HDAC8 HDAC9 HDAC10 HDAC11 HD1 HD2

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Description

OKI-006 is an orally active histone deacetylase (HDAC) inhibitor. OKI-006 is the active metabolite of OKI-005 (HY-185584) and OKI-179 (HY-156602). OKI-006 can be used for the research of cancers such as breast cancer and colorectal cancer[1].

In Vitro

OKI-006 potently and selectively inhibits HDAC-1, HDAC-2, HDAC-3, HDAC-8, HDAC-6, HDAC-10, and HDAC-11, with IC50 values of 1.2, 2.4, 2, 47, 47, 2.8, and 2.3 nM, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

OKI-006 Related Antibodies
Molecular Weight

482.62

Formula

C21H30N4O5S2
CAS No.
SMILES

SCC/C=C/[C@@H]1CC(NCC2=NC(C(NC(C)(C(N[C@H](C(O1)=O)C(C)C)=O)C)=O)=CS2)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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OKI-006 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

OKI-0061315334-23-6OKI006OKI 006HDACHistone deacetylasesHDAC inhibitorHDAC-1HDAC-2HDAC-3HDAC-8HDAC-6HDAC-10HDAC-11Inhibitorinhibitorinhibit

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