PROTAC BRD4 Degrader-20
PROTAC BRD4 Degrader-20 (Compound 195) is a PROTAC degrader that targets BRD4 for degradation by recruiting VHL. PROTAC BRD4 Degrader-20 is applicable to the research of diffuse large B-cell lymphoma.
(Pink: BRD4 ligand (HY-78695); Blue: VHL ligand (HY-112078); Black: linker (HY-175582)).
For research use only. We do not sell to patients.
- CAS No.: 2086300-61-8
- Formula: C55H58ClN9O7S2
- Molecular Weight:1056.69
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Biological Activity
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BRD4 |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:CB17 SCID mice bearing SU-DHL-6 xenografts[1]
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Dosage:6 mg/kg
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Administration:i.v.; every 3 days
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Result:Induced tumor regression.
Chemical Information
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CAS No. 2086300-61-8
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Molecular Weight 1056.69
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Formula C55H58ClN9O7S2
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SMILES
CC1=C(C)SC2=C1C(C3=CC=C(C=C3)Cl)=N[C@@H](CC(N[C@H]4C[C@H](C4)OC5=CC=C(OC(C(N[C@@H](C(C)(C)C)C(N6[C@@H](C[C@H](C6)O)C(N[C@H](C7=CC=C(C8=C(N=CS8)C)C=C7)C)=O)=O)=O)=C9)C9=C5)=O)C%10=NN=C(C)N2%10
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PROTAC BRD4 Degrader-20 Related Classifications
HY-153820 Related Classifications
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