PROTAC BRD4 Degrader-34
PROTAC BRD4 Degrader-34 (Compound MZ2) is a selective BRD4 PROTAC degrader (pDC50 = 8.4). PROTAC BRD4 Degrader-34 can induce BD2 degradation mediated by VHL. PROTAC BRD4 Degrader-34 can be used for research on cancer. (Pink: BRD4-BD2 Ligand (HY-78695); Blue: VHL Ligand (HY-125845); Black: Linker (HY-130524)).
(Pink: BRD4 ligand (HY-78695); Blue: VHL ligand (HY-125845); Black: linker (HY-130524)).
For research use only. We do not sell to patients.
- CAS No.: 1797406-70-2
- Formula: C51H64ClN9O9S2
- Molecular Weight:1046.69
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Biological Activity
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VHL |
BRD4 BD2 |
Chemical Information
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CAS No. 1797406-70-2
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Molecular Weight 1046.69
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Formula C51H64ClN9O9S2
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SMILES
CC1=C(C2=CC=C(CNC([C@@H]3C[C@@H](O)CN3C([C@H](C(C)(C)C)NC(COCCOCCOCCOCCNC(C[C@@H]4N=C(C5=CC=C(Cl)C=C5)C(C(C)=C(C)S6)=C6N7C4=NN=C7C)=O)=O)=O)=O)C=C2)SC=N1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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