PROTAC EZH2 Degrader-14
PROTAC EZH2 Degrader-14 is an EZH2 PROTAC degrader, with an IC50 of 18.21 μM against diffuse large B-cell lymphoma cells, and exhibits no antiproliferative activity against non-target cells at concentrations up to 30.00 μM. PROTAC EZH2 Degrader-14 can be used in studies related to diffuse large B-cell lymphoma.
(Pink: EZH2 ligand (HY-147230); Blue: Cereblon ligand (HY-14658); Black: linker).
For research use only. We do not sell to patients.
- CAS No.: 3093642-21-5
- Formula: C58H71N11O11
- Molecular Weight:1098.25
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 3093642-21-5
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Molecular Weight 1098.25
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Formula C58H71N11O11
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SMILES
CCN(C1=CC(C2=CC=C(CN3CCN(C(C4=CN(N=N4)CCOCCOCCOCCNC5=C6C(C(N(C6=O)C7CCC(NC7=O)=O)=O)=CC=C5)=O)CC3)C=C2)=CC(C(NCC8=C(C)C=C(C)NC8=O)=O)=C1C)C9CCOCC9
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)