PROTAC EZH2 Degrader-40
PROTAC EZH2 Degrader-40 (compound 56) is a PROTAC protein degrader targeting EZH2 with an IC50 of 15.35 μM against SU-DHL-6 cells. PROTAC EZH2 Degrader-40 can be used for the research of diffuse large B-cell lymphoma.
(Pink: EZH2 ligand (HY-147230); Blue: cIAP ligand (HY-137159); Black: linker).
For research use only. We do not sell to patients.
- CAS No.: 3093642-40-8
- Formula: C61H85N11O9
- Molecular Weight:1116.40
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
Chemical Information
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CAS No. 3093642-40-8
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Molecular Weight 1116.40
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Formula C61H85N11O9
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SMILES
CCN(C1CCOCC1)C2=CC(C3=CC=C(C=C3)CN4CCN(CC4)C(CCC5=CN(N=N5)CCOCCOCCNC([C@H](CC(C)C)NC([C@@H](O)[C@H](N)CC6=CC=CC=C6)=O)=O)=O)=CC(C(NCC7=C(C=C(NC7=O)C)C)=O)=C2C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PROTAC EZH2 Degrader-40 Related Classifications
HY-181409 Related Classifications
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