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Pulocimab

(Synonyms: AK109)
Customer Review

Based on 1 Customer Validation

Pulocimab (AK109) is an orally active PPARα/γ dual activator with EC50 values of 48 nM and 67 nM, respectively. Pulocimab reduces plasma glucose, improves dyslipidemia, lowers total cholesterol, and raises HDL cholesterol. Pulocimab binds VEGFR2 and blocks VEGF/VEGFR2 signaling, inhibiting angiogenesis, endothelial cell migration, and tumor cell proliferation. Pulocimab can be used for research on type 2 diabetes with dyslipidemia and advanced or metastatic solid tumors.

For research use only. We do not sell to patients.

  • Purity : 98.42%
  • CAS No.: 2428381-49-9
  • Molecular Weight:143.721 kDa
  • Storage:
    Shipping with dry ice

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Pulocimab
  • Experimental Validation Results for Pulocimab
  • Pulocimab Chemical Structure
    Pulocimab Chemical Structure
CAS No.: 2428381-49-9
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Pulocimab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
  • Biological Activity
  • Chemical Information
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  • Purity & Documentation
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Top Publications Citing

Use of MCE Products

All PPAR Isoforms

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All VEGFR Isoforms

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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Immobilized VEGFR-2 Protein, Human (HEK293, His, HY-P70552) can bind Pulocimab. The EC50 for this effect is 19.88 ng/mL.

  • Pulocimab Chemical Structure
    1/16
  • Pulocimab
  • Immobilized VEGFR-2 Protein, Human (HEK293, His, HY-P70552) can bind Pulocimab. The EC50 for this effect is 19.88 ng/mL.