13114 Results for "

fixed mouse brain tissue

" in MedChemExpress (MCE) Product Catalog:
Products (13114)

13114 Results for "fixed mouse brain tissue" in MCE Product Catalog:

96
96 Cited Publications
Cat. No.: HY-15608
CAS No.: 23007-85-4
Purity:  99.52%
MPTP hydrochloride is a brain penetrant dopaminergic neurotoxin. MPTP hydrochloride can be used to induce Parkinson’s Disease model. MPTP hydrochloride, a precusor of MPP +, induces apoptosis . MPTP hydrochloride has been verified by MCE with professional biological experiments.
loading...
    loading...
75
75 Cited Publications
Cat. No.: HY-B0318
CAS No.: 443-48-1
Metronidazole is an orally active nitroimidazole antibiotic. Metronidazole can cross blood brain barrier. Metronidazole can be used for the research of anaerobic infections .
loading...
    loading...
75
75 Cited Publications
Cat. No.: HY-B0318A
CAS No.: 69198-10-3
Synonyms: SC 326421
Metronidazole hydrochloride (SC 326421) is an orally active nitroimidazole antibiotic, can be used to research anaerobic infections. Metronidazole hydrochloride can cross blood brain barrier and results inflammation and skeletal muscle contraction under long-term application .
loading...
    loading...
71
71 Cited Publications
Cat. No.: HY-P7117
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TGFB1; Transforming Growth Factor Beta1; Prev. TGFB; Camurati-Engelmann Disease; Prev. DPD1; Latency-Associated Peptide; TGFbeta; TGF-Beta-1; CED; TGF-Beta1; Transforming Growth Factor Beta-1 Proprotein; IBDIMDE; Prepro-Transforming Growth Factor Beta-1;
Species:  
Rat Mouse
Source:  
HEK293
loading...
    loading...
70
70 Cited Publications
Cat. No.: HY-N0003
CAS No.: 35354-74-6
Synonyms: NSC 293100
Honokiol is a bioactive, biphenolic phytochemical that possesses potent antioxidative, anti-inflammatory, antiangiogenic, and anticancer activities by targeting a variety of signaling molecules. It inhibits the activation of Akt. Honokiol can readily cross the blood brain barrier .
loading...
    loading...
68
68 Cited Publications
Cat. No.: HY-A0276A
CAS No.: 1403-66-3
Gentamicin, an aminoglycoside antibiotic, inhibits the growth of both gram-positive and gram-negative bacteria and to inhibit several strains of mycoplasma in tissue culture. Gentamicin inhibits DNase I with an IC50 of 0.57 mM .
loading...
    loading...
68
68 Cited Publications
Cat. No.: HY-A0276
CAS No.: 1405-41-0
Gentamicin sulfate, an aminoglycoside antibiotic, inhibits the growth of both gram-positive and gram-negative bacteria and to inhibit several strains of mycoplasma in tissue culture. Gentamicin sulfate inhibits DNase I with an IC50 of 0.57 mM .
loading...
    loading...
61
61 Cited Publications
Cat. No.: HY-100347A
CAS No.: 2070014-88-7
Purity:  99.55%
Target:  

TGF-beta/Smad

Research Areas:  

Neurological Disease

SRI-011381 hydrochloride is an orally active TGF-β signaling agonist, exhibits neuroprotective effects, with blood-brain barrier permeability .
loading...
    loading...
60
60 Cited Publications
Cat. No.: HY-B0356B
CAS No.: 86393-32-0
Synonyms: Bay-09867 hydrochloride monohydrate
Ciprofloxacin (Bay-09867) hydrochloride monohydrate is an orally active, blood-brain barrier permeable fluoroquinolone antibacterial agent. Ciprofloxacin hydrochloride monohydrate exerts bactericidal effects primarily by inhibiting topoisomerase II and IV. Ciprofloxacin hydrochloride monohydrate inhibits the proliferation of human dental pulp stem cells and chondrocytes from young rats, and also activates the Akt signaling pathway and upregulates markers such as β-catenin and Nanog to maintain the morphological characteristics of stem cells. Ciprofloxacin hydrochloride monohydrate induces significant neurotoxicity and tissue damage, including reducing serotonin and glutathione levels in the brain, inducing oxidative stress and depression-like behaviors, and causing articular cartilage damage. Ciprofloxacin hydrochloride monohydrate can be applied to research related to infections of necrotic young permanent teeth and neurotoxicity .
loading...
    loading...
60
60 Cited Publications
Cat. No.: HY-B0356A
CAS No.: 93107-08-5
Synonyms: Bay-09867 monohydrochloride
Ciprofloxacin (Bay-09867) monohydrochloride is an orally active, blood-brain barrier permeable fluoroquinolone antibacterial agent. Ciprofloxacin monohydrochloride exerts bactericidal effects primarily by inhibiting topoisomerase II and IV. Ciprofloxacin monohydrochloride inhibits the proliferation of human dental pulp stem cells and chondrocytes from young rats, and also activates the Akt signaling pathway and upregulates markers such as β-catenin and Nanog to maintain the morphological characteristics of stem cells. Ciprofloxacin monohydrochloride induces significant neurotoxicity and tissue damage, including reducing serotonin and glutathione levels in the brain, inducing oxidative stress and depression-like behaviors, and causing articular cartilage damage. Ciprofloxacin monohydrochloride can be applied to research related to infections of necrotic young permanent teeth and neurotoxicity .
loading...
    loading...
59
59 Cited Publications
Cat. No.: HY-100614
CAS No.: 919486-40-1
Purity:  98.99%
Target:  

STAT

Research Areas:  

Inflammation/Immunology Cancer

AS1517499 is a potent and brain-permeable STAT6 phosphorylation inhibitor with an IC50 of 21 nM.
loading...
    loading...
58
58 Cited Publications
Cat. No.: HY-13909
CAS No.: 1357389-11-7
Purity:  99.81%
Target:  

HDAC

Research Areas:  

Cancer

RGFP966 is a highly selective HDAC3 inhibitor with an IC50 of 80 nM and shows no inhibition to other HDACs at concentrations up to 15 μM. RGFP966 can penetrate the blood brain barrier (BBB).
loading...
    loading...
57
57 Cited Publications
Cat. No.: HY-P7080
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL4; B_cell Stimulatory Factor 1; Interleukin 4; B-Cell Stimulatory Factor 1; IL-4; B Cell Growth Factor 1; Lymphocyte Stimulatory Factor 1; Binetrakin; Interleukin-4; Pitrakinra; BCGF-1; MGC79402; BCGF1; BSF-1; BSF1
Species:  
Mouse
Source:  
CHO
loading...
    loading...
55
55 Cited Publications
Cat. No.: HY-P7071
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IFNG; IMD69; Interferon Gamma; IFG; IFN-Gamma; IFI; Immune Interferon
Species:  
Mouse
Source:  
E. coli
loading...
    loading...
52
52 Cited Publications
Cat. No.: HY-15084
CAS No.: 77086-22-7
Purity:  99.99%
Synonyms: (+)-MK 801 Maleate
Target:  

iGluR

Research Areas:  

Neurological Disease

Dizocilpine maleate (MK-801 maleate) is a potent, selective and non-competitive NMDA receptor antagonist with Kd of 37.2 nM in rat brain membranes.
loading...
    loading...
51
51 Cited Publications
Cat. No.: HY-B2167
CAS No.: 6217-54-5
Synonyms: DHA; Cervonic acid
Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. It can be obtained directly from fish oil and maternal milk.
loading...
    loading...
50
50 Cited Publications
Cat. No.: HY-B0099
CAS No.: 89-25-8
Synonyms: MCI-186
Edaravone is a strong novel free radical scavenger, and inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator.
loading...
    loading...
48
48 Cited Publications
Cat. No.: HY-P7073
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1B; IL-1B; Interleukin 1 Beta; Multifunctional Fusion Protein; IL1F2; Pro-Interleukin-1-Beta; Interleukin-1 Beta; Preinterleukin 1 Beta; IL1-BETA; Interleukin 1beta; IL-1 Beta; IL1beta; Catabolin; IL-1
Species:  
Mouse
Source:  
E. coli
loading...
    loading...
46
46 Cited Publications
Cat. No.: HY-B1473
CAS No.: 153-98-0
Synonyms: 5-Hydroxytryptamine hydrochloride; 5-HT hydrochloride
Serotonin (5-Hydroxytryptamine) hydrochloride is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist, with blood-brain barrier permeability. Serotonin hydrochloride is also a catechol O-methyltransferase (COMT) inhibitor with a Ki of 44 μM.
loading...
    loading...
45
45 Cited Publications
Cat. No.: HY-P7361
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF2; Molgramostim; Colony Stimulating Factor 2; Molgramostin; GMCSF; CSF; Sargramostim; Granulocyte-Macrophage Colony Stimulating Factor; GM-CSF; Granulocyte Macrophage-Colony Stimulating Factor; Colony Stimulating Factor 2 (Granulocyte-Macrophage); Colo
Species:  
Mouse
Source:  
E. coli
loading...
    loading...