9106 Results for "

Cardiovascular

" in MedChemExpress (MCE) Product Catalog:
Products (9106)

9106 Results for "Cardiovascular" in MCE Product Catalog:

136
136 Cited Publications
Cat. No.: HY-P1410
CAS No.: 1209500-46-8
GsMTx4 is a spider venom peptide that selectively inhibits cationic-permeable mechanosensitive channels (MSCs) belonging to the Piezo and TRP channel families. GsMTx4 also blocks cation-selective stretch-activated channels (SACs) , attenuates lysophosphatidylcholine (LPC)-induced astrocyte toxicity and microglial reactivity. GsMTx4 is an important pharmacological tool for identifying the role of these excitatory MSCs in normal physiology and pathology .
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136
136 Cited Publications
Cat. No.: HY-P1410A
GsMTx4 TFA is a spider venom peptide that selectively inhibits cationic-permeable mechanosensitive channels (MSCs) belonging to the Piezo and TRP channel families. GsMTx4 TFA also blocks cation-selective stretch-activated channels (SACs) , attenuates lysophosphatidylcholine (LPC)-induced astrocyte toxicity and microglial reactivity. GsMTx4 TFA is an important pharmacological tool for identifying the role of these excitatory MSCs in normal physiology and pathology .
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124
124 Cited Publications
Cat. No.: HY-N0830
CAS No.: 57-10-3
Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. PA can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells. Palmitic acid is used to establish a cell steatosis model .
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120
120 Cited Publications
Cat. No.: HY-18723
CAS No.: 448947-81-7
Domaines de recherche:  

Cardiovascular Disease

Yoda 1 is a potent and selective Piezo1 agonist. Yoda 1 activates purified Piezo1 channels. Yoda 1 potently inhibits macropinocytosis induced by epidermal growth factor (EGF). Yoda 1 enhances Ca 2+ influx followed by activation of the calcium-activated potassium channel KCa3.1 and inhibition of Rac1 activation .
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117
117 Cited Publications
Cat. No.: HY-10231
CAS No.: 685898-44-6
Pureté:  ≥98.0%
PX-478 is a multifunctional HIF-1α inhibitor with properties including radiosensitization, autophagy activation, and lipid accumulation inhibition. PX-478 also blocks hypoxia-induced VEGF production and regulates β-cell phenotypes under hypoxic conditions. PX-478 induces cell cycle arrest and DNA damage, restores autophagic function, reduces foam cell formation, and maintains glucose homeostasis. PX-478 is widely used in research on related diseases such as human tumors (e.g., prostate cancer), type 2 diabetes, and atherosclerosis .
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97
97 Cited Publications
Cat. No.: HY-108353
CAS No.: 7683-59-2
Target:  

Adrenergic Receptor

Domaines de recherche:  

Cardiovascular Disease Endocrinology

Isoprenaline is a non-selective, orally active β-adrenergic receptor agonist. Isoprenaline has potent peripheral vasodilator, bronchodilator, and cardiac stimulating activities. Isoprenaline can be used for the research of bradycardia and bronchial asthma .
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97
97 Cited Publications
Cat. No.: HY-108353A
CAS No.: 299-95-6
Isoprenaline hemisulfate is a non-selective, orally active β-adrenergic receptor agonist. Isoprenaline has potent peripheral vasodilator, bronchodilator, and cardiac stimulating activities. Isoprenaline can be used for the research of bradycardia and bronchial asthma .
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97
97 Cited Publications
Cat. No.: HY-B0468
CAS No.: 51-30-9
Synonyms: Isoproterenol hydrochloride
Isoprenaline (Isoproterenol) hydrochloride is a non-selective, orally active β-adrenergic receptor agonist. Isoprenaline has potent peripheral vasodilator, bronchodilator, and cardiac stimulating activities. Isoprenaline can be used for the research of bradycardia and bronchial asthma .
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96
96 Cited Publications
Cat. No.: HY-N0322A
Target:  

Liposome

Cholesterol Water Soluble is a major sterol in mammals, constituting 20-25% of the structural composition of the plasma membrane. The plasma membrane is highly permeable to water but relatively impermeable to ions and protons. Cholesterol Water Soluble plays an important role in determining the fluidity and permeability characteristics of membranes and the function of transporters and signaling proteins. Cholesterol Water Soluble is also an endogenous estrogen-related receptor alpha (ERRα) agonist. Cholesterol Water Soluble can be used to study the effects of cholesterol on potassium currents in inner hair cells .
(Note: This product is a mixture of Cholesterol and Methyl-β-cyclodextrin. The product specifications below only indicate the effective content of Cholesterol.)
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96
96 Cited Publications
Cat. No.: HY-N0322
CAS No.: 57-88-5
Cholesterol (from animal) is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol (from animal) plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins . Cholesterol (from animal) is also an endogenous estrogen-related receptor α (ERRα) agonist .
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95
95 Cited Publications
Cat. No.: HY-A0064
CAS No.: 152-11-4
Synonyms: (±)-Verapamil hydrochloride; CP-16533-1 hydrochloride
Verapamil hydrochloride ((±)-Verapamil hydrochloride) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Verapamil hydrochloride also inhibits CYP3A4. Verapamil hydrochloride has the potential for high blood pressure, heart arrhythmias and angina research .
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95
95 Cited Publications
Cat. No.: HY-14275
CAS No.: 52-53-9
Pureté:  98.96%
Synonyms: (±)-Verapamil; CP-16533-1
Verapamil ((±)-Verapamil) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Verapamil also inhibits CYP3A4. Verapamil has the potential for high blood pressure, heart arrhythmias and angina research .
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94
94 Cited Publications
Cat. No.: HY-19424
CAS No.: 16009-13-5
Synonyms: Hemin chloride
Hemin is an iron-containing porphyrin. Hemin is an Heme oxygenase (HO)-1 inducer.
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90
90 Cited Publications
Cat. No.: HY-17502
CAS No.: 79902-63-9
Synonyms: MK 733
Simvastatin (MK 733) is a competitive inhibitor of HMG-CoA reductase with a Ki of 0.2 nM.
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82
82 Cited Publications
Cat. No.: HY-W009724
CAS No.: 524-95-8
Synonyms: 2-APB
2-Aminoethyl diphenylborinate (2-APB) is a cell-permeable inhibitor of Inositol triphosphate receptor (IP3R). 2-Aminoethyl diphenylborinate also inhibits the store-operated Ca 2+ (SOC) channel and activates some TRP channels (V1, V2 and V3). Additionally, 2-Aminoethyl diphenylborinate has inhibitory effects on vasospasm. At high concentrations, it exhibits specific anti-inflammatory and antioxidant effects in neural tissue .
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80
80 Cited Publications
Cat. No.: HY-N0716B
CAS No.: 633-66-9
Synonyms: Natural Yellow 18 sulfate
Berberine sulfate is an alkaloid isolated from the Chinese herbal medicine Huanglian, as an antibiotic. Berberine sulfate induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Berberine sulfate has antineoplastic properties. The sulfate form improves bioavailability .
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79
79 Cited Publications
Cat. No.: HY-13715
CAS No.: 51-41-2
Pureté:  99.61%
Synonyms: Levarterenol; L-Noradrenaline
Norepinephrine (Levarterenol; L-Noradrenaline) is a potent adrenergic receptor (AR) agonist. Norepinephrine activates α1, α2, β1 receptors .
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79
79 Cited Publications
Cat. No.: HY-13715B
CAS No.: 108341-18-0
Pureté:  99.96%
Synonyms: Levarterenol bitartrate monohydrate; L-Noradrenaline bitartrate monohydrate
Norepinephrine (Levarterenol; L-Noradrenaline) bitartrate monohydrate is a potent adrenergic receptor (AR) agonist. Norepinephrine activates α1, α2, β1 receptors .
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79
79 Cited Publications
Cat. No.: HY-13715C
CAS No.: 51-40-1
Pureté:  99.76%
Synonyms: Levarterenol tartrate; L-Noradrenaline tartrate
Norepinephrine (Levarterenol; L-Noradrenaline) tartrate is a potent adrenergic receptor (AR) agonist. Norepinephrine tartrate activates α1, α2, β1 receptors .
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79
79 Cited Publications
Cat. No.: HY-13715A
CAS No.: 329-56-6
Pureté:  99.89%
Synonyms: Levarterenol hydrochloride; L-Noradrenaline hydrochloride
Norepinephrine (Levarterenol; L-Noradrenaline) hydrochloride is a potent adrenergic receptor (AR) agonist. Norepinephrine activates α1, α2, β1 receptors .
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