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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
553 Results for "
AGEs
" in MedChemExpress (MCE) Product Catalog:
Products (553)
553 Results for "AGEs" in MCE Product Catalog:
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1 Cited Publications
Cat. No.: HY-W013573
CAS No.: 21593-77-1
Category:
Natural Products Neurological Disease Anti-aging Metabolic Disease Allium sativum Linn. Plants Liliaceae Extract Disease Research Fields Inflammation/Immunology Cancer
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1 Cited Publications
Cat. No.: HY-16959
CAS No.: 816432-15-2
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Cardiovascular Disease Infection Animals Marine natural products Other marine organisms Disease Research Fields Steroids
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AG-13958 (AG-013958), a potent VEGFR tyrosine kinase inhibitor, is used for treatment of choroidal neovascularization associated with age-related macular degeneration (AMD) .
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Tenilsetam (CAS 997) is an antidementia compound. Tenilsetam is an advanced glycation end product (AGE) inhibitor. Tenilsetam inhibits early retinopathy in experimental diabetes rats .
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1 Cited Publications
Cat. No.: HY-N7628
CAS No.: 119170-52-4
Synonyms: Toralactone 9-O-β-D-gentiobioside
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Cassia tora (L.) Roxb. Monophenols Metabolic Disease Phenols Leguminosae Extract Plants Disease Research Fields
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Rheum palmatum L. Stilbenes Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology Polygonaceae Extract
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1 Cited Publications
Synonyms: HL271; IM156 hydrochloride; HL156A hydrochloride
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Lixumistat (IM156) hydrochloride is a potent and orally active AMPK activator and OXPHOS inhibitor. Lixumistat hydrochloride strongly activates AMPK, while it lacks the systemic metabolic regulatory effects of classic metformin, such as hypoglycemic and weight-lowering activities. Lixumistat hydrochloride exhibits significant therapeutic effects on cognitive decline associated with brain aging and pulmonary fibrosis .
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1 Cited Publications
Synonyms: IM156; HL156A; HL271 acetate
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Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Lixumistat (IM156) acetate is a potent and orally active AMPK activator and OXPHOS inhibitor. Lixumistat acetate strongly activates AMPK, while it lacks the systemic metabolic regulatory effects of classic metformin, such as hypoglycemic and weight-lowering activities. Lixumistat acetate exhibits significant therapeutic effects on cognitive decline associated with brain aging and pulmonary fibrosis .
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1 Cited Publications
Cat. No.: HY-136093B
CAS No.: 1422365-93-2
Synonyms: IM156 free base; HL156A free base; HL271 free base
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Lixumistat (IM156 free base) is a potent and orally active AMPK activator and OXPHOS inhibitor. Lixumistat strongly activates AMPK, while it lacks the systemic metabolic regulatory effects of classic metformin, such as hypoglycemic and weight-lowering activities. Lixumistat exhibits significant therapeutic effects on cognitive decline associated with brain aging and pulmonary fibrosis .
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Acrizanib (LHA510) is a small-molecule vascular endothelial growth factor receptor 2 (VEGFR-2, KDR) inhibitor. Acrizanib inhibits the proliferation of BaF3-Tel-KDR cells dependent on VEGFR-2 activity, with an IC50 of 17.4 nM. Acrizanib can be used in research related to choroidal neovascularization and neovascular age-related macular degeneration .
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1 Cited Publications
Cat. No.: HY-N3026
CAS No.: 118194-13-1
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1 Cited Publications
Cat. No.: HY-W001083
CAS No.: 621-37-4
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S 17092 (S 17092-1) is an orally active cerebral prolyl-endopeptidase (PEP) inhibitor with an IC50 of 1.2 nM. S 17092 inhibits cell apoptosis. S 17092 mechanism of action is to inhibit the activity of PEP, slowing down the degradation of neuroactive peptides and thus enhancing memory function. S 17092 can be used for the research of memory impairment and cognitive disorders associated with cerebral aging .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
