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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1101 Results for "
Anticancer agent
" in MedChemExpress (MCE) Product Catalog:
Products (1101)
1101 Results for "Anticancer agent" in MCE Product Catalog:
Cat. No.: HY-167825
CAS No.: 24506-68-1
Cat. No.: HY-179098
Multi-target kinase-IN-8 (3d) is an anti-cancer agent. Multi-target kinase-IN-8 exhibits inhibitory activity against various protein kinases (B-Raf V600E (IC50 = 0.078 µg/mL), c-Met (IC50 = 0.405 µg/mL), Pim-1 (IC50 = 1.053 µg/mL), EGFR WT (IC50 = 0.177 µg/mL), VEGFR-2 (IC50 = 0.275 µg/mL)). Multi-target kinase-IN-8 can induce cell cycle arrest and promote early and late apoptosis. Multi-target kinase-IN-8 is commonly used in cancer research .
Cat. No.: HY-B0166S8
CAS No.: 1331939-77-5
Synonyms: L-Ascorbate-1; Vitamin C-13C6-1
Cat. No.: HY-N0176S
CAS No.: 176774-98-4
Synonyms: Dihydroqinghaosu-d3; β-Dihydroartemisinin-d3; Artenimol-d3
Cat. No.: HY-N0176S3
Synonyms: Dihydroqinghaosu-d5; β-Dihydroartemisinin-d5; Artenimol-d5
Target:
Cat. No.: HY-N17550
CAS No.: 173740-54-0
Cat. No.: HY-W106860R
CAS No.: 51761-07-0
Synonyms: 3-Formylcarbazole (Standard)
Target:
Cat. No.: HY-W777393
CAS No.: 1189992-05-9
Synonyms: 7-Hydroxycoumarin-13C6; Hydrangin-13C6; NSC 19790-13C6
Cat. No.: HY-Z11709
CAS No.: 1160974-39-9
Target:
Cat. No.: HY-155882
CAS No.: 80506-64-5
Synonyms: mPEG750-NH2
Synonyms: Ru(η6-p-cymene)Cl2(pta)
Research Areas:
RAPTA-C (Ru(η6-p-cymene)Cl2(pta)) acts as an anti-cancer and anti-angiogenic agent. RAPTA-C exhibits anti-metastatic, anti-angiogenic, and anti-tumoral activities through protein and histone-deoxyribonucleic acid alterations. RAPTA-C exhibits cell growth inhibition by triggering G(2)/M phase arrest in cancer cells. RAPTA-C also enhances the levels of p53 and triggers the mitochondrial Apoptotic pathway, resulting in cytochrome C release and caspase-9 activation. RAPTA-C reduces the growth of tumors with the inhibition of angiogenesis in a ovarian carcinoma model .
Cat. No.: HY-145432
CAS No.: 2747100-02-1
PI3K-IN-28 (Compound 6c) is a potent inhibitor of PI3K. PI3K-IN-28 displays the most potent activity with lower toxic effects on MCF-10a. PI3K-IN-28 displays half-maximal inhibitory concentration (IC50, μM) values of 5.8, 2.3, and 7.9. PI3K-IN-28 is the most potent one with a selectivity index (SI) of 39 and is considered as a latent lead for further optimization of anticancer agents .
Cat. No.: HY-19896A
CAS No.: 1204956-74-0
Target:
Research Areas:
COTI-2 hydrochloride is an orally active thiosemicarbazone anticancer agent and p53 mutant activator. COTI-2 hydrochloride induces Apoptosis. COTI-2 hydrochloride triggers the activation of AMPK and the inhibition of the mTOR pathway. COTI-2 hydrochloride induces DNA damage and replication stress responses. COTI-2 hydrochloride binds to misfolded mutant p53 proteins, thereby inducing conformational changes that restore p53 to its normal state and reactivate its function. COTI-2 hydrochloride acts on a variety of cancer cell lines and xenografts. COTI-2 hydrochloride can be used in research related to colorectal cancer, small cell lung cancer, glioblastoma, breast cancer, and ovarian cancer .
Cat. No.: HY-B0914AR
CAS No.: 557-08-4
Synonyms: Zinc undecylenate (Standard)
Category:
Category:
Cat. No.: HY-W005255R
CAS No.: 621-54-5
Cat. No.: HY-W017424
CAS No.: 136-95-8
Target:
Research Areas:
2-Aminobenzothiazole acts as a caspase 3/7 activator, an anticancer cytotoxic agent, and also exhibits neurotoxicity. 2-Aminobenzothiazole drives the apoptotic pathway by activating caspase 3/7, induces mitochondrial inner membrane depolarization, and triggers both early and late apoptosis via a caspase-dependent pathway. In zebrafish models, 2-Aminobenzothiazole induces oxidative damage in brain tissues and inhibits genes related to GABA and 5-HT synthesis pathways. Long-term exposure to 2-Aminobenzothiazole impairs motor ability, social behavior, anxiety-like state and cognitive function. 2-Aminobenzothiazole can be used in studies of human laryngeal carcinoma and related neurotoxicity .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
