175 Results for "

PTP1B

" in MedChemExpress (MCE) Product Catalog:
Products (175)

175 Results for "PTP1B" in MCE Product Catalog:

Cat. No.: HY-N17424
CAS No.: 83474-71-9
Mulberrofuran D is a protein tyrosine phosphatase 1B (PTP1B) inhibitor, with an IC50 of 11.61 μM and a Ki of 4.79 μM against human PTP1B. Mulberrofuran D can be used in research related to type 2 diabetes [1].
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Cat. No.: HY-182483
CAS No.: 237756-11-5
Target:  

Phosphatase

Research Areas:  

Metabolic Disease

Ethyl-3,4-dephostatin is a Protein tyrosine phosphatase 1B (PTP1B) inhibitor with an IC50 of 0.58 μg/mL. Ethyl-3,4-dephostatin can be used in studies of PTP1B-related enzyme inhibition mechanisms [1].
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Cat. No.: HY-N14540
CAS No.: 1253641-15-4
Glycybenzofuran is a flavonoid. Glycybenzofuran can be isolated from G. uralensis. Glycybenzofuran is a potent, competitive, selective PTP1B inhibitor. Glycybenzofuran shows excellent inhibitory selectivity against PTP1B. Glycybenzofuran increases insulin-stimulated pAkt levels. Glycylbenzofuran can be used in the research of hepatocellular carcinoma [1] .
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Cat. No.: HY-N20416
Category:  

Extract

Target:  

Phosphatase

Sambucus adnata extract is an extract of Sambucus adnata that has significant protein tyrosine phosphatase 1B (PTP1B) inhibitory activity.
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Cat. No.: HY-N17455
CAS No.: 84323-14-8
Albafuran A (Compound 1/4) is a protein tyrosine phosphatase 1B (PTP1B) inhibitor and can be used in research related to type 2 diabetes and obesity [1] .
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Cat. No.: HY-N19225
CAS No.: 6360-94-7
3-Glyceroylindole (Compound 17) is a monoindole alkaloid with no significant inhibitory activity against protein tyrosine phosphatase 1b (PTP1B), and its IC50 is > 20 μM [1].
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Cat. No.: HY-N17326
CAS No.: 242794-72-5
Ilekudinol B is an inhibitor of ACAT and PTP1B, with an IC50 of 5.3 μM and a Ki of 11.6 μM against human PTP1B. Ilekudinol B inhibits the classical pathway of the complement system, with an IC50 of 51 μM. Ilekudinol B inhibits TNF-α-induced cellular IL-8 secretion, promotes glucose uptake in skeletal muscle myotubes, and acts as an insulin mimetic and insulin sensitizer. Ilekudinol B can be used in research related to type 2 diabetes, obesity, and inflammatory diseases [1] .
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Cat. No.: HY-N17642
CAS No.: 1402543-98-9
Arhododendric acid A (Compound 1) is a triterpenoid found in Rhododendron brachycarpum. Arhododendric acid A can inhibit PTP1B with an IC50 of 6.3 μM. Arhododendric acid A can be used for the research of type 2 diabetes [1].
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Cat. No.: HY-N19131
CAS No.: 160219-85-2
Aquastatin B is a PTP1B inhibitor. Aquastatin B is isolated from marine fungi. Aquastatin B exhibits anti-diabetic activity. Aquastatin B can be used in the research of diabetes [1].
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Cat. No.: HY-N16588A
CAS No.: 1085706-33-7
trans-Emodin-physcion bianthrone is a protein tyrosine phosphatase 1B (PTP1B) inhibitor with an IC50 of 2.77 μM. trans-Emodin-physcion bianthrone is applicable to research related to insulin resistance [1].
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Cat. No.: HY-N18297
CAS No.: 202815-28-9
Licoagrochalcone A is a PTP1B inhibitor. Licoagrochalcone A exerts protective effects against liver cell injury induced by carbon tetrachloride and Acetaminophen (HY-66005). Licoagrochalcone A is applicable to the research of type 2 diabetes, obesity and liver injury [1].
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Cat. No.: HY-N8200
CAS No.: 218155-40-9
Cassiaside B2 is a protein tyrosine phosphatase 1B (PTP1B) and human monoamine oxidase A (hMAO-A) inhibitor. Cassiaside B2 possesses antiallergic and is a 5-HT2C receptor agonist [1] . ..
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Cat. No.: HY-123966
CAS No.: 2204280-41-9
Purity:  98.84%
Target:  

Phosphatase

Research Areas:  

Neurological Disease

MY33-3 is a potent and selective inhibitor of receptor protein tyrosine phosphatase (RPTP)β/ζ, with an IC50 of ~0.1 μM. MY33-3 also inhibits PTP-1B (IC50 ~0.7 μM). MY33-3 can reduce ethanol consumption and alleviate Sevoflurane-induced neuroinflammation and cognitive dysfunction [1] .
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Cat. No.: HY-123966A
CAS No.: 2204280-42-0
Purity:  99.32%
Target:  

Phosphatase

Research Areas:  

Neurological Disease

MY33-3 hydrochloride is a potent and selective inhibitor of receptor protein tyrosine phosphatase (RPTP)β/ζ, with an IC50 of ~0.1 μM. MY33-3 hydrochloride also inhibits PTP-1B (IC50 ~0.7 μM). MY33-3 hydrochloride can reduce ethanol consumption and alleviate Sevoflurane-induced neuroinflammation and cognitive dysfunction [1] .
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Cat. No.: HY-120901
CAS No.: 1143579-78-5
Target:  

SHP2 SHP1

Research Areas:  

Cancer

II-B08 is a reversible and noncompetitive SHP2 inhibitor (IC50: 5.5 μM, 15.7, 14.3 μM for SHP2, SHP1, PTP1B). II-B08 can be used for cancer research [1].
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Cat. No.: HY-N7599
CAS No.: 120181-07-9
Chrysophanol triglucoside is an anthraquinone isolated from Cassia obtusifolia, inhibits protein tyrosine phosphatases 1B (PTP1B) and α-glucosidase with IC50s of 80.17 and 197.06 µM, respectively. Chrysophanol triglucoside has the potential for diabetes research [1].
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Cat. No.: HY-P1799
CAS No.: 159453-08-4
Target:  

Phosphatase

Research Areas:  

Others

[pTyr5] EGFR (988-993) is derived from the autophosphorylation site (Tyr992) of epidermal growth factor receptor (EGFR 988-993). [pTyr5] EGFR (988-993) is often complexed with the catalytically inactive protein-tyrosine phosphate 1B (PTP1B) [1].
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Cat. No.: HY-N10378
CAS No.: 132922-80-6
Rubrofusarin 6-O-β-D-glucopyranoside, the glycoside of Rubrofusarin, is a protein tyrosine phosphatase 1B (PTP1B) inhibitor with the IC50 of 87.36 μM. Rubrofusarin 6-O-β-D-glucopyranoside can be used for the research of comorbid diabetes and depression [1].
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Cat. No.: HY-N8282
CAS No.: 523-73-9
Flavoglaucin is a compound that exhibits significant anti-tumor promoting activity. Flavoglaucin exhibits significant inhibition of PTP1B with an IC50 value of 13.4 micromolar. Flavoglaucin also shows good binding affinity to human opioid or cannabinoid receptors. Flavoglaucin has anti-inflammatory activity [1].
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Cat. No.: HY-N11441
CAS No.: 94942-20-8
cis-Ferulic acid 4-O-β-D-glucopyranoside (compound 7) is a phenolic glycosid, which can be isolated from Nitraria sibirica.. cis-Ferulic acid 4-O-β-D-glucopyranoside exhibits antioxidant activity and potent inhibitory effect on Phosphatase PTP1B [1].
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