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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
61 Results for "
4-anilino quinazoline
" in MedChemExpress (MCE) Product Catalog:
Products (61)
61 Results for "4-anilino quinazoline" in MCE Product Catalog:
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9 Publications Verification
Cat. No.: HY-B0371F
CAS No.: 63074-08-8
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Terazosin hydrochloride is a quinazoline derivative and a competitive and orally active α1-adrenoceptor antagonist. Terazosin hydrochloride works by relaxing blood vessels and the opening of the bladder. Terazosin hydrochloride has the potential for benign prostatic hyperplasia (BPH) and high blood pressure treatment .
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9 Publications Verification
Cat. No.: HY-B0371
CAS No.: 63590-64-7
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9 Publications Verification
Cat. No.: HY-B0371A
CAS No.: 70024-40-7
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Terazosin hydrochloride dihydrate is a quinazoline derivative and a competitive and orally active α1-adrenoceptor antagonist. Terazosin hydrochloride dihydrate works by relaxing blood vessels and the opening of the bladder. Terazosin hydrochloride dihydrate has the potential for benign prostatic hyperplasia (BPH) and high blood pressure treatment .
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8 Cited Publications
Cat. No.: HY-N6607
CAS No.: 13220-57-0
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Doxazosin mesylate (UK 33274 mesylate) is a quinazoline-derivative that selectively antagonizes postsynaptic α1-adrenergic receptors.
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3 Cited Publications
Synonyms: AST-1306 (TsOH)
Allitinib tosylate (AST-1306 (TsOH)) is an orally active and irreversible EGFR and ErbB2 inhibitor with IC50s of 0.5 and 3 nM, respectively. Allitinib tosylate also inhibits ErbB4 with an IC50 of 0.8 nM. Allitinib tosylate is an anilino-quinazoline compound and has anti-cancer activity
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3 Cited Publications
Synonyms: AST-1306; ALS 1306
Allitinib (AST-1306) is an orally active and irreversible EGFR and ErbB2 inhibitor with IC50s of 0.5 and 3 nM, respectively. Allitinib also inhibits ErbB4 with an IC50 of 0.8 nM. Allitinib is an anilino-quinazoline compound and has anti-cancer activity .
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Acanthaceae Extract Alkaloids Pyrrole Alkaloids Alfredia cernua (L.) Cass. Plants Disease Research Fields Inflammation/Immunology
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Zygophyllaceae Extract Alfredia cernua (L.) Cass. Peganum harmala Linn. Plants Infection Acanthaceae Extract Alkaloids Other Alkaloids Disease Research Fields Inflammation/Immunology
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1 Cited Publications
Cat. No.: HY-W749874
CAS No.: 97457-31-3
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Acanthaceae Extract Flavonoids Plants Other Flavonoids Jacobaea cannabifolia (Less.) E. Wiebe
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Acanthaceae Extract Alkaloids Pyrrole Alkaloids Neurological Disease Alfredia cernua (L.) Cass. Plants Other Families Extract Disease Research Fields
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ND-011992 is a reversible, selective quinazoline-type inhibitor targeting quinone reductases and quinol oxidases. ND-011992 inhibits respiratory complex I and bo3 oxidase in addition to bd-I and bd-II oxidases in E. coli strain BL21*Δcyo with the IC50 of 0.12, 2.47, 0.63 and 1.3 μM, respectively. ND-011992 can be used for tuberculosis study .
WHI-P258, a quinazoline compound, binds to the active site of JAK3 with an estimated Ki of 72 µM. WHI-P258 does not inhibit JAK3 and does not affect the thrombin-induced aggregation of platelets even at 100 μM .
Cat. No.: HY-Y0260
CAS No.: 13790-39-1
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4-Chloro-6,7-dimethoxyquinazoline is a quinazoline derivative. 4-Chloro-6,7-dimethoxyquinazoline exhibits a significant interaction with the AChE protein (as demonstrated by molecular docking analysis). 4-Chloro-6,7-dimethoxyquinazoline is applicable to research related to Alzheimer's disease .
Cat. No.: HY-W012071
CAS No.: 16652-71-4
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(S)-Benzyl pyrrolidine-2-carboxylate hydrochloride is an intermediate in the synthesis of L-proline derivative peptides. (S)-Benzyl pyrrolidine-2-carboxylate hydrochloride is a key raw material for the synthesis of apoptosis inhibitor protein (IAP) antagonists and SMAC mimic tripeptide fragments (Boc-MeAla-Tle-Pro-OH). (S)-Benzyl pyrrolidine-2-carboxylate hydrochloride can be used to synthesize divalent quinazoline IAP antagonists .
Synonyms: XDE-436; EL-436
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Fenazaquin (XDE-436; EL-436) is a quinazoline acaricide .
Cat. No.: HY-N6607R
CAS No.: 13220-57-0
Cat. No.: HY-B0371S
CAS No.: 1006718-20-2
hVEGF-IN-1, a quinazoline derivative, could specifically bind to the G-rich sequence in the internal ribosome entry site A (IRES-A) and destabilize the G-quadruplex structure. hVEGF-IN-1 binds to the IRES-A (WT) with a Kd of 0.928 μM in SPR experiments. hVEGF-IN-1 could hinder tumor cells migration and repress tumor growth by decreasing VEGF-A protein expression .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
