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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
51 Results for "
Adipogenic
" in MedChemExpress (MCE) Product Catalog:
Products (51)
51 Results for "Adipogenic" in MCE Product Catalog:
11
11 Publications Verification
Synonyms: Genistine; Genistoside; Genistein 7-O-β-D-glucopyranoside
Category:
Flavonoids Glycine max (L.) merr Metabolic Disease Phenols Polyphenols Leguminosae Extract Plants Disease Research Fields Isoflavones
Target:
9
9 Cited Publications
Cat. No.: HY-N1411
CAS No.: 58479-68-8
9
9 Cited Publications
Research Areas:
E6446 dihydrochloride is a potent and orally acitve TLR7 and TLR9 antagonist, used in the research of deleterious inflammatory responses. E6446 dihydrochloride is also a potent SCD1 inhibitor (KD: 4.61 μM), significantly inhibiting adipogenic differentiation and hepatic lipogenesis through SCD1-ATF3 signaling. E6446 dihydrochloride also improves liver pathology in high-fat diet (HFD)-fed mice and may be useful in the study of non-alcoholic fatty liver disease (NAFLD) .
9
9 Cited Publications
Research Areas:
E6446 is a potent and orally acitve TLR7 and TLR9 antagonist, used in the research of deleterious inflammatory responses. E6446 is also a potent SCD1 inhibitor (KD: 4.61 μM), significantly inhibiting adipogenic differentiation and hepatic lipogenesis through SCD1-ATF3 signaling. E6446 also improves liver pathology in high-fat diet (HFD)-fed mice and may be useful in the study of non-alcoholic fatty liver disease (NAFLD) .
6
6 Cited Publications
Target:
Research Areas:
Pyrintegrin is an β1-integrin agonist and a 2,4-disubstituted pyrimidine that promotes embryonic stem cells survival. Pyrintegrin enhances cell-extracellular matrix (ECM) adhesion-mediated integrin signaling. Pyrintegrin can be used as a podocyte-protective agent and has robustly adipogenic .
6
6 Cited Publications
Target:
Research Areas:
AS2863619 is an orally active CDK8/19 inhibitor that also inhibits BMP2, MDA5 and RIG-I receptors. AS2863619 targets Stat5a-CDK8/19 to promote the differentiation of CD4 + T cells into regulatory T cells and induce FOXP3 expression, thereby restoring immune homeostasis and establishing transplant immune tolerance. AS2863619 also enhances the BMP2/SMAD signaling pathway to promote osteogenic differentiation and inhibit adipogenic differentiation. AS2863619 exerts osteoprotective effects by alleviating inflammation-induced impairment of osteogenic function and inducing neutrophil apoptosis (apoptosis). AS2863619 can be applied to research in related fields such as periodontitis-induced bone defects .
6
6 Cited Publications
Target:
Research Areas:
AS2863619 free base is an orally active CDK8/19 inhibitor that also inhibits BMP2, MDA5 and RIG-I receptors. AS2863619 free base targets Stat5a-CDK8/19 to promote the differentiation of CD4 + T cells into regulatory T cells and induce FOXP3 expression, thereby restoring immune homeostasis and establishing transplant immune tolerance. AS2863619 free base also enhances the BMP2/SMAD signaling pathway to promote osteogenic differentiation and inhibit adipogenic differentiation. AS2863619 free base exerts osteoprotective effects by alleviating inflammation-induced impairment of osteogenic function and inducing neutrophil apoptosis (apoptosis). AS2863619 free base can be applied to research in related fields such as periodontitis-induced bone defects .
3
3 Cited Publications
Cat. No.: HY-N4103
CAS No.: 17605-67-3
Category:
Target:
2
2 Cited Publications
Cat. No.: HY-N0526
CAS No.: 53209-27-1
1
1 Cited Publications
Cat. No.: HY-N0704
CAS No.: 55576-66-4
1
1 Cited Publications
Synonyms: (-)-Eudesmin; Eudesmine; (-)-Eudesmine
Category:
Infection Lignans Metabolic Disease Magnolia Liliflora Desr. Phenylpropanoids Plants Magnoliaceae Extract Disease Research Fields Inflammation/Immunology
Target:
1
1 Cited Publications
Cat. No.: HY-N3027
CAS No.: 117230-33-8
Category:
Triterpenes Glycine max (L.) merr Terpenoids Metabolic Disease Leguminosae Extract Plants Disease Research Fields
Target:
1
1 Cited Publications
Cat. No.: HY-N4253
CAS No.: 173792-61-5
Cat. No.: HY-77641
CAS No.: 16534-24-0
Category:
Microorganisms Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields
Target:
Cat. No.: HY-N1984
CAS No.: 80286-58-4
Synonyms: Qing Hao acid; Artemisinic acid; Arteannuic acid
Category:
Infection Terpenoids Sesquiterpenes Artemisia carvifolia Buch.-Ham. ex Roxb. Metabolic Disease Plants Compositae Extract Disease Research Fields Inflammation/Immunology
Target:
Target:
Research Areas:
6-Thioinosine (6TI) is a purine antimetabolite and an anti-adipogenic agent. 6-Thioinosine reduces the mRNA levels of PPARγ and C/EBPα and downregulates the mRNA levels of PPARγ target genes (LPL, CD36, aP2, and LXRα). 6-Thioinosine exerts its anti-adipogenic effects by downregulating PPARγ through JNK-dependent iNOS upregulation. 6-Thioinosine can be used to study adipocyte dysfunction .
Target:
Research Areas:
Tricalcium phosphate is a calcium-phosphorus compound mainly composed of calcium ions and phosphate (PO4 3-). Tricalcium phosphate promotes osteogenic differentiation, inhibits adipogenic and chondrogenic differentiation, and serves as a scaffold for spinal fusion implants. Tricalcium phosphate supports reparative dentin formation, mineralized nodule formation, and calcium ion release. Tricalcium phosphate is commonly used in fields such as biomaterials, bone repair, food additives, and pharmaceutical preparations .
Synonyms: N-FMOC-leucine-d3; NPC 15199-d3; NSC 334290-d3
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
