353 Results for "

MilD

" in MedChemExpress (MCE) Product Catalog:
Products (353)

353 Results for "MilD" in MCE Product Catalog:

45
45 Publications Verification
Cat. No.: HY-B1530
CAS No.: 515-98-0
Synonyms: (±)-Ammonium lactate
Research Areas:  

Infection

Ammonium lactate is the ammonium salt of lactic acid, with mild anti-bacterial properties. Ammonium lactate can be used for the research of xerosis .
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25
25 Cited Publications
Cat. No.: HY-N4000
CAS No.: 11024-24-1
Digitonin, a glycoside obtained from Digitalis purpurea, could increase cell permeability by binding to cholesterol molecules and reduce tumor growth . Digitonin is an natural detergent .
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17
17 Cited Publications
Cat. No.: HY-50682
CAS No.: 603148-36-3
Synonyms: TTP488; PF-04494700
Target:  

Amyloid-β

Research Areas:  

Neurological Disease Cancer

Azeliragon (TTP488) is an orally bioavailable inhibitor of the receptor for advanced glycation end products (RAGE) in development as a potential treatment to slow disease progression with mild Alzheimer’s disease (AD) . Azeliragon also can cross the blood-brain barrier (BBB) .
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16
16 Cited Publications
Cat. No.: HY-K1002

MCE NP-40 Lysis Buffer is a relatively mild reliable buffers used to lyse cells from animal, plant tissue and fungi, bacteria etc.

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9
9 Cited Publications
Cat. No.: HY-13005
CAS No.: 53185-12-9
Purity:  98.97%
Synonyms: D-Fagomine
Fagomine is a mild glycosidase inhibitor. The Ki of the iminosugar Fagomine is 4.8 μM, 39 μM, and 70 μM for Amyloglucosidase (A.niger), β-Glucosidase (bovine), and Isomaltase (yeast), respectively.
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8
8 Cited Publications
Cat. No.: HY-W017389
CAS No.: 69-89-6
Xanthine, a plant alkaloid found in tea, coffee, and cocoa, is a mild stimulant of the central nervous system. Xanthine also acts as an intermediate product on the pathway of purine degradation .
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7
7 Cited Publications
Cat. No.: HY-B0575
CAS No.: 396-01-0
Triamterene blocks epithelial Na + channel (ENaC) in a voltage-dependent manner, which used as a mild diuretic. Triamterene is an inhibitor of the TGR5 receptor .
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5
5 Cited Publications
Cat. No.: HY-10199A
CAS No.: 159634-47-6
Purity:  98.52%
Synonyms: MK-677 free base; MK-0677 free base
Ibutamoren (MK-677 free base; MK-0677 free base) is an orally active non-peptide growth hormone secretagogue receptor agonist. Ibutamoren activates signal cascades by mimicking endogenous ligands, triggers pulsatile release of growth hormone from the pituitary gland, and increases serum levels of IGF-1 and insulin-like growth factor-binding protein 3. Ibutamoren not only increases the frequency of growth hormone pulses in male individuals, but also promotes elevated bone formation markers in female individuals with postmenopausal osteoporosis. The combination of Ibutamoren with Alendronate sodium hydrate (HY-11101) significantly increases bone mineral density at the femoral neck. However, Ibutamoren may cause mild, reversible adverse reactions such as increased appetite, fluid retention, and elevated fasting blood glucose. Ibutamoren has been widely used in studies related to idiopathic growth hormone deficiency, sarcopenia, Alzheimer's disease, and osteoporosis .
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3
3 Cited Publications
Cat. No.: HY-B0892
CAS No.: 100-51-6
Synonyms: Benzenemethanol
Benzyl alcohol is an aromatic alcohol, a colorless liquid with a mild aromatic odor. Benzyl alcohol is an inhibitor of P450 enzyme. Benzyl alcohol mediated Toll-Like Receptor 4 to reduce the inflammatory response of liver injury in mice .
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3
3 Cited Publications
Cat. No.: HY-109085
CAS No.: 937782-05-3
Purity:  99.63%
Synonyms: OPA-15406
Difamilast (OPA-15406) is a topical, selective and nonsteroidal phosphodiesterase-4 (PDE4) inhibitor with particularly efficient inhibition of subtype B (IC50=11.2 nM). Difamilast can be used for the research of mild to moderate atopic dermatitis (AD) .
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3
3 Cited Publications
Cat. No.: HY-N0265
CAS No.: 39524-08-8
Synonyms: Akebia saponin D
Asperosaponin VI is a saponin component from Dipsacus asper. Asperosaponin VI induces osteoblast differentiation through the BMP-2/p38 and ERK1/2 signaling pathways. Asperosaponin VI protects against hypoxia-induced cardiomyocyte apoptosis by activating the PI3K/Akt and CREB pathways. Additionally, Asperosaponin VI also has antidepressant and wound-healing-promoting activities .
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2
2 Cited Publications
Cat. No.: HY-10933
CAS No.: 154235-83-3
Purity:  99.94%
Synonyms: BDP 12
Target:  

iGluR

Research Areas:  

Neurological Disease

CX516 (BDP 12) is an ampakine and acts as an AMPA receptor positive allosteric modulator for the research of Alzheimer's disease, schizophrenia and mild cognitive impairment (MCI) .
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2
2 Cited Publications
Cat. No.: HY-129524
CAS No.: 4672-49-5
Purity:  ≥98.0%
Target:  

Apoptosis

Research Areas:  

Inflammation/Immunology

Ethylene dimethane sulfonate is a mild alkylating, non-volatile methanesulfonic diester of ethylene glycol. Ethylene dimethanesulfonate has selective pro-apoptotic effects on LCs .
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2
2 Cited Publications
Cat. No.: HY-108243
CAS No.: 1034148-04-3
Purity:  99.85%
AZD5423 is an inhaled, potent, selective, and non-steroidal glucocorticoid receptor (GR) modulator (SGRM) . AZD5423 effectively reduces allergen-induced responses in subjects with mild allergic asthma .
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1
1 Cited Publications
Cat. No.: HY-B1147
CAS No.: 3736-81-0
Target:  

Parasite

Research Areas:  

Infection

Diloxanide furoate is the proagent of Diloxanide. Diloxanide furoate is a potent and orally active anti-protozoal agent and can be used for the research of amebiasis, mild intestinal amebiasis or asymptomatic cyst carriers .
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1
1 Cited Publications
Cat. No.: HY-N5107
CAS No.: 41689-51-4
Synonyms: (+)-epi-Magnolin
Epimagnolin A, a furfuran lignan, shows mild antiplasmodial activities (IC50=5.7 μg/mL) without noticeable toxicity on mammalian normal cells .
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1
1 Cited Publications
Cat. No.: HY-34619
CAS No.: 27126-76-7
[Hydroxy(tosyloxy)iodo]benzene is a versatile reagent for the mild oxidation of aryl iodides at the iodine atom by ligand transfer. [Hydroxy(tosyloxy)iodo]benzene is an effective reagent for the one-step conversion of ketones to the corresponding α-tosyloxy ketones. [Hydroxy(tosyloxy)iodo]benzene is also a Bronsted acid and is expected to catalyze the enolization of ketones .
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1
1 Cited Publications
Cat. No.: HY-17368
CAS No.: 123441-03-2
Synonyms: ENA 713 free base; SDZ-ENA 713 free base
Target:  

Cholinesterase (ChE)

Research Areas:  

Neurological Disease

Rivastigmine (ENA 713 free base) is an orally active and potent cholinesterase (ChE) inhibitor and inhibits butyrylcholinesterase (BChE) and acetylcholinesteras (AChE) with IC50s of 0.037 μM , 4.15 μM, respectively. Rivastigmine can pass the blood brain barrier (BBB). Rivastigmine is a parasympathomimetic or cholinergic agent used for the research of mild to moderate dementia of the Alzheimer's type and dementia due to Parkinson's disease .
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1
1 Cited Publications
Cat. No.: HY-P99103
CAS No.: 2578319-11-4
Synonyms: LY-3853113; LY-COV1404

Target:  

SARS-CoV

Research Areas:  

Infection

Bebtelovimab a human IgG1-λ2 antibody targeting to SARS-CoV-2, especially COVID-19 ((the IC50 value for SARS-CoV-2/MT020880.1 virus is 9-22.1 ng/mL)). Bebtelovimab potently neutralizes SARS-CoV-2 variants, and inhibits COVID-19 with mild-to-moderate efficacy .
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1
1 Cited Publications
Cat. No.: HY-Z0478
CAS No.: 5989-54-8
Synonyms: (S)-(-)-Limonene
(-)-Limonene ((S)-(-)-Limonene) is orally active and can cause mild bronchoconstriction. (-)-Limonene alleviates cytosolic and mitochondrial oxidative stress by inhibiting the increase of calcium ions (Ca 2+) and Ca 2+/calmodulin-dependent protein kinase II (CaMKII). It also exerts anti-stress effects by inhibiting the activity of the hypothalamic-pituitary-adrenal (HPA) axis. Additionally, (-)-Limonene can be used as an antibacterial agent in aquaculture .
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