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Probes

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154

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-D0080
    Laurdan
    20+ Cited Publications

    Fluorescent Dye Others
    Laurdan is a membrane-permeable fluorescent probe that displays spectral sensitivity to the phospholipid phase of the cell membrane to which it is bound. Quantitation of generalized polarization (GP) of Laurdan can be used to identify phospholipid phase (Ex/Em = 370/440-490 nm).
    Laurdan
  • HY-D0908

    Fluorescent Dye Others
    Ninhydrin can be used as a chromogenic analytical probe for the quantification of amino acids and proteins.
    Ninhydrin
  • HY-B1025
    Digoxigenin
    1 Publications Verification

    Lanadigenin

    Fluorescent Dye Inflammation/Immunology
    Digoxigenin (DIG) is a steroid. DIG is used for situ hybridization as a labeling molecule probe due to long shelf life and fast detection and high sensitivity of DIG-labeled riboprobes .
    Digoxigenin
  • HY-135136

    Biochemical Assay Reagents Fluorescent Dye Others
    Aldehyde reactive probe TFA is an aldehyde reactive probe. Aldehyde reactive probe TFA specifically labels the AP site in DNA with biotin residues. Aldehyde reactive probe TFA can detect RNA oxidation-induced debasement sites. Aldehyde reactive probe TFA can be used to quantify AP sites or detect other aldehyde-containing DNA damage and RNA oxidation-induced debasement sites .
    Aldehyde reactive probe TFA
  • HY-W111141

    endo-9-Hydroxymethylbicyclo[6.1.0]non-4-yne

    Biochemical Assay Reagents Others
    BCN-OH (endo-9-Hydroxymethylbicyclo[6.1.0]non-4-yne) is an alcohol functionalized cyclooctyne derivative. BCN-OH can act as a raw material for synthesizing other probes (such as BCN-TPP). BCN-OH is used to construct targeted probes by coupling with carboxyl-containing compounds (such as TPP-COOH). BCN-OH can be used as control reagent for BCN-TPP .
    BCN-OH
  • HY-D1458

    Fluorescent Dye Cardiovascular Disease Neurological Disease Cancer
    Peroxyfluor 1 is a cell-permeable probe for H2O2. Peroxyfluor 1 represents a first-generation, green-fluorescent probe .
    Peroxyfluor 1
  • HY-D0133

    Fluorescent Dye Others
    NBD-X acid is a fluorescent probe containing a nitrobenzoxadiazole group. NBD-X acid can be used to study the structure and function of biomolecules .
    NBD-X acid
  • HY-D0807
    5-IAF
    1 Publications Verification

    5-Iodoacetamidofluorescein

    Fluorescent Dye Cancer
    5-IAF (5-Iodoacetamidofluorescein) is an idoacetamide derivate of fluoresceine. 5-IAF can be used as fluorescent probe that labels proteins and other molecules having free thiols (cysteine side chains) .
    5-IAF
  • HY-115691

    Styrene-BODIPY; Styrene-Conjugated BODIPY

    Fluorescent Dye Others
    STY-BODIPY (Styrene-BODIPY; Styrene-Conjugated BODIPY) is a styrene-conjugated fluorescent probe used to measure the activity of radical-trapping antioxidants (RTAs)> .
    STY-BODIPY
  • HY-DY1025

    Fluorescent Dye Others
    Laurdan (solution) is a membrane-permeable fluorescent probe that displays spectral sensitivity to the phospholipid phase of the cell membrane to which it is bound. Quantitation of generalized polarization (GP) of Laurdan can be used to identify phospholipid phase.
    Solvent and concentration: DMSO: 5 mM
    Laurdan (solution)
  • HY-D1046

    Dabcyl, SE

    Fluorescent Dye Others
    Dabcyl acid, SE is the amine-reactive form of Dabcyl acid (DABCYL) (HY-D1045), and is widely used in the preparation of fluorescent probes containing DABCYL .
    Dabcyl acid, SE
  • HY-W088089

    Fluorescent Dye Cancer
    ICG-carboxylic acid is near-infrared (NIR) fluorescent probe. ICG is a fluorescent dye used in medical diagnostics. ICG has absorption peaking at 800 nm and can absorb the near IR laser energy and release heat in the dyed tissue (Ex/Em = 785/810 nm) .
    ICG-carboxylic acid
  • HY-DY1044

    Bacterial Infection
    HADA hydrochloride (HCC-Amino-D-alanine hydrochloride) is a blue (λem~450 nm) fluorescent D-amino acid (FDAA). FDAAs are efficiently incorporated into the peptidoglycans (PGs) of diverse bacterial species at the sites of PG biosynthesis, allowing specific and covalent probing of bacterial growth with minimal perturbation .
    Solvent and concentration: DMSO: 50 mM
    HADA hydrochloride (solution)
  • HY-W013967

    Fluorescent Dye Infection
    1,6-Diphenylhexa-1,3,5-triene is a membrane intercalator and hydrophobic fluorescent probe. 1,6-Diphenylhexa-1,3,5-triene intercalates into the non-polar region of lipid bilayers of adipocyte membranes with probe/membrane equilibrium affected by temperature, probe concentration, and membrane concentration. 1,6-Diphenylhexa-1,3,5-triene’s fluorescence intensity correlating with adipocyte membrane probe incorporation (Ex/Em = 350/452 nm) .
    1,6-Diphenylhexa-1,3,5-triene
  • HY-D1148
    HKGreen-4I
    1 Publications Verification

    Fluorescent Dye Others
    HKGreen-4I is a highly sensitive green fluorescent probe for the specific detection of ONOO - in living cells with a maximum excitation wavelength and emission wavelength of 520 nm and 543 nm, respectively .
    HKGreen-4I
  • HY-D0127

    Fluorescent Dye Others
    Merocyanin 540 is a fluorescent membrane probe that selectively stains the membranes of a wide variety of electrically excitable cells, but not those of nonexcitable cells (Ex/Em: 540/580 nm) .
    Merocyanin 540
  • HY-147652

    DNA Stain Others
    G-quadruplex DNA fluorescence probe 1 (Compound E1) is a selective G-quadruplex DNA targeting fluorescent probe. G-quadruplex DNA fluorescence probe 1 can pass through membrane and enter living cells with low cytotoxicity .
    G-quadruplex DNA fluorescence probe 1
  • HY-130015
    HKSOX-1 (5/6-mixture)
    2 Publications Verification

    Reactive Oxygen Species (ROS) Others
    HKSOX-1 (5/6-mixture) is a fluorescent probe which is used for imaging and detection of endogenous superoxide in live cells and in vivo. HKSOX-1 (5/6-mixture) exhibits excellent selectivity and sensitivity towards superoxide anion radical (Ex/Em = 509/534 nm) .
    HKSOX-1 (5/6-mixture)
  • HY-130017

    Reactive Oxygen Species (ROS) Others
    HKSOX-1r (5/6-mixture) is a fluorescent probe which is used for imaging and detection of endogenous superoxide in live cells and in vivo. HKSOX-1r (5/6-mixture) exhibits excellent selectivity and sensitivity towards superoxide anion radical .
    HKSOX-1r (5/6-mixture)
  • HY-162160

    Fluorescent Dye Others
    NR12S is a fluorescence probe. NR12S can be used for the research of studying cholesterol and lipid order in biomembranes .
    NR12S
  • HY-D2329

    Fluorescent Dye Others
    Fluorescein-PEG4-NHS ester is a colorimetric probe formed by the reaction of adipic dihydrazide and fluorescein isothiocyanate .
    Fluorescein-PEG4-NHS ester
  • HY-D0941
    5-Carboxytetramethylrhodamine
    1 Publications Verification

    Fluorescent Dye Others
    5-Carboxytetramethylrhodamine can be used as a fluorescent probe of nucleic acids and proteins. 5-Carboxytetramethylrhodamine displays excitation maxima of 558 nm and an emission maximum of 586 nm .
    5-Carboxytetramethylrhodamine
  • HY-D2312

    Fluorescent Dye Ferroptosis Cancer
    Mito-Rh-S is a ratiometric near-infrared (NIR) fluorescent probe that detects the fluctuation of mitochondrial HClO levels during ferroptosis in hepatocellular carcinoma (HCC) .
    Mito-Rh-S
  • HY-D1252
    Fast-TRFS
    2 Publications Verification

    Fluorescent Dye Others
    Fast-TRFS is a selective and superfast fluorogenic probe of thioredoxin reductase (TrxR). Fast-TRFS can be used for imaging TrxR activity in live cells .
    Fast-TRFS
  • HY-133080

    GnRH Receptor Cancer
    BAY-784 is a gonadotropin releasing hormone receptor (GnRH-R) antagonist probe with IC50s of 21 and 24 nM for human and rat GnRH-R, respectively .
    BAY-784
  • HY-124197

    Fluorescent Dye Others
    Coumarin hydrazine is a fluorescent chemical probeex=420–450/λem=468nm) to label cellular protein- and lipid-bound carbonyls .
    Coumarin hydrazine
  • HY-138065

    Apoptosis Others
    Iodoacetyl-LC-biotin is a biotinylated electrophile probe that can be used to investigate the scope and characteristics of protein covalent binding to subcellular proteomes .
    Iodoacetyl-LC-biotin
  • HY-D0896A
    ANS ammonium
    1 Publications Verification

    NSC 1746 ammonium; Peri acid, phenyl- ammonium; Phenyl peri acid ammonium

    Bacterial Infection
    ANS ammonium is a potent antibacterial agent and a textile dye. ANS ammonium can be used as fluorescence probe. ANS ammonium blocks the binding of triiodothyronine to thyroxine binding globulin in radioimmunoassay of triiodothyronine .
    ANS ammonium
  • HY-W040681

    Fluorescent Dye Others
    7-Dimethylaminocoumarin-4-acetic acid is a fluorescent probe .
    7-Dimethylaminocoumarin-4-acetic acid
  • HY-D2912

    Biochemical Assay Reagents Others
    Cys-shift probe-1 (compound 13) is a potent Cys-shift probe. Cys-shift probe-1 can improve the ion mobility of labeled peptides and be used in protein analysis .
    Cys-shift probe-1
  • HY-D1022A

    Biotin-16-deoxyuridine-5'-triphosphate trisodium

    DNA Stain Others
    Biotin-16- dUTP (Biotin-16-deoxyuridine-5'-triphosphate) trisodium can be used to replace its natural counterpart dTTP by enzymatically incorporating it into DNA/cDNA. Biotin-16- dUTP trisodium can be used to produce biotinylated DNA probes in a variety of assay applications .
    Biotin-16-dUTP trisodium
  • HY-D1151
    HKOH-1
    3 Publications Verification

    Reactive Oxygen Species (ROS) Fluorescent Dye Others
    HKOH-1 is a highly sensitive green fluorescent probe for the specific detection of ·OH in living cells with a maximum excitation wavelength and emission wavelength of 500 nm and 520 nm, respectively .
    HKOH-1
  • HY-W069127F

    Bio-ben

    Biochemical Assay Reagents Others
    Biotin-benzoboroxole (Bio-ben) is a functional probe for the detection of cysteine sulfenic acid (Cys-SOH) .
    Biotin-benzoboroxole
  • HY-D1265
    EtS-DMAB
    2 Publications Verification

    HClO-green

    Fluorescent Dye Others
    EtS-DMAB (HClO-green) is a fluorescent probe, which can selectively detect hypochlorous acid (HOCl) (λex=440 nm, λem=610 nm). EtS-DMAB is applied to image exogenous and endogenous HOCl in live cells .
    EtS-DMAB
  • HY-147889

    Apoptosis Caspase Bcl-2 Family Others
    BBR-BODIPY is a fluorescent probe that allows screening its interaction with the targeted cells. BBR-BODIPY induces apoptosis and changes the expression of apoptosis-related proteins .
    BBR-BODIPY
  • HY-136957

    Fluorescent Dye Others
    Fluorescein-6-isothiocyanate is a fluorescent isomeric haptenic probes with Kds of 8.74, 2.72 and 1.88 for N-Acetyl-L-Lysine, normal mouse IgG and 4-4-20, respectively .
    Fluorescein-6-isothiocyanate
  • HY-D1478

    Fluorescent Dye Others
    Fluorescent polyamine probe-1 (compound 15) is a linear polyamine probe with high uptake efficiency. Fluorescent polyamine probe-1 can be used for the research of transport system into cancer cells .
    Fluorescent polyamine probe-1
  • HY-D2418

    Fluorescent Dye Metabolic Disease
    PS-SCOTfluor-12 (compound 10) is a fluorescent probe for imaging Lactic acid (HY-B2227) metabolism in live cells. λex/λem= 485/605 nm .
    PS-SCOTfluor-12
  • HY-130013

    Fluorescent Dye Others
    HKYellow-AM (6/12-mixture) is a yellow fluorescent probe that can detect ONOO- in living cells and tissues with high selectivity and sensitivity without cytotoxicity .
    HKYellow-AM (6/12-mixture)
  • HY-D1022

    Biotin-16-deoxyuridine-5'-triphosphate

    Fluorescent Dye Others
    Biotin-16-dUTP (Biotin-16-deoxyuridine-5'-triphosphate) can be used to replace its natural counterpart dTTP by enzymatically incorporating it into DNA/cDNA. Biotin-16- dUTP can be used to produce biotinylated DNA probes in a variety of assay applications .
    Biotin-16-dUTP
  • HY-D1631A

    Fluorescent Dye Neurological Disease
    Calcium green-5N hexapotassium is a cell-impermeant Ca 2+-sensitive fluorescent probe. Calcium green-5N hexapotassium shows enhancement in fluorescence intensity on binding Ca 2+, and can monitor free Ca 2+ in neurons .
    Calcium green-5N hexapotassium
  • HY-D1107

    PARP Others
    NCT-TFP is PARP probe used to identifying Poly(ADP-ribose) polymerases (PARP) inhibitors (extracted from patent US20190331688A1) .
    NCT-TFP
  • HY-130022
    HKPerox-1
    2 Publications Verification

    Fluorescent Dye Others
    HKPerox-1 is a highly sensitive green fluorescent probe for the specific detection of H2O2 in living cells with a maximum excitation wavelength and emission wavelength of 520 nm and 543 nm, respectively .
    HKPerox-1
  • HY-130027
    HKOCl-4
    1 Publications Verification

    BXY2142

    Fluorescent Dye Others
    HKOCl-4 (BXY2142) is a rhodol-based yellow fluorescent probe for the detection of hypochlorous acid with excellent sensitivity and selectivity . HKOCl-4 has longer absorption wavelength and better pH stability compared with fluorescein-based probes. Ex: 530 nm; Em 557 nm.
    HKOCl-4
  • HY-151890

    Fluorescent Dye Cancer
    NIR-βgal-2 is a β-galactosidase-activated near-infrared fluorescent probe with superior sensitivity. NIR-βgal-2 can be used for visualizing β-galactosidase in breast cancer .
    NIR-βgal-2
  • HY-D1254

    NBL-SS perchlorate

    Fluorescent Dye Others
    Trx-red (NBL-SS perchlorate) is a red-emitting fluorescent probe derivatized from the nile blue fluorophore. Trx-red is used for selectively imaging thioredoxin (Trx) in live cells and in vivo (λex=615 nm, λem=661 nm) .
    Trx-red
  • HY-D2267

    Fluorescent Dye Others
    JF646-Hoechst is a fluorescent red DNA probe that is an ideal substitute for large oligonucleotide-coupled antibodies used in PAINT experiments, especially for bacterial studies. JF646-Hoechst excitation/emission maximum =655/670 nm .
    JF646-Hoechst
  • HY-D1188

    PARP Cancer
    PARP7-probe-1 is a chemiluminescent labeled PARP7 probe. PARP7-probe-1 is a biotinylated probe binding to the PARP7 active site. PARP7-probe-1 can be used for the research of PARP7 function .
    PARP7-probe-1
  • HY-D2377

    Fluorescent Dye Others
    F8 is a small molecule GPR84 fluorescent probe that can visualize and detect GPR84 protein levels at the cellular and tissue levels .
    F8
  • HY-P3791

    Fluorescent Dye Others
    N-Succinyl-Ile-Ile-Trp-AMC is a peptide-based fluorescent substrate or probe for carboxypeptidase Y (CPY) .
    N-Succinyl-Ile-Ile-Trp-AMC

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