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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
102 Results for "
and immune regulation
" in MedChemExpress (MCE) Product Catalog:
Products (102)
102 Results for "and immune regulation" in MCE Product Catalog:
23
Category:
Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite
Target:
12
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12
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9
9 Cited Publications
Cat. No.: HY-N6653
CAS No.: 37339-90-5
Category:
Polysaccharides Agaricaceae Extract Lentinus edodes (Berk. ) Sing Plants Disease Research Fields Saccharides Cancer
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8
8
8 Cited Publications
Cat. No.: HY-P1934
CAS No.: 14705-60-3
Synonyms: Cyclo(phenylalanylprolyl); A-64863
Research Areas:
6
6 Cited Publications
Cat. No.: HY-N0587
CAS No.: 107316-88-1
5
3
2
2 Cited Publications
Cat. No.: HY-148980A
CAS No.: 33378-44-8
Target:
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Polyinosinic acid sodium is the sodium form of Polyinosinic acid (HY-148980). Polyinosinic acid is a single stranded homonucleic acid, which is a Toll-like Receptor 3 (TLR3) ligand. Polyinosinic acid enhances cellular immune response through TLR3 and TRIF. Polyinosinic acid has potential applications in immune regulation .
2
2 Cited Publications
Cat. No.: HY-P5641
CAS No.: 190324-47-1
Research Areas:
1
1 Cited Publications
Synonyms: 7-Sulfocholic acid
Research Areas:
Cholic acid 7-sulfate (7-Sulfocholic acid) is a selective agonist targeting TGR5 (EC50=0.17 μM) and a ligand for MHC class I-related protein (MR1). As a gut-restricted TGR5 agonist, cholic acid 7-sulfate binds to TGR5 on enteroendocrine L cells, induces GLP-1 secretion, and improves glucose tolerance in a TGR5-dependent manner. Cholic acid 7-sulfate also acts as an endogenous ligand for MR1, promoting the survival of mucosal-associated invariant T cells MAIT and the expression of homeostatic gene signatures, affecting MAIT cell development and function. Cholic acid 7-sulfate is mainly used in the research of diabetes and MAIT cell-related immune regulation .
1
Target:
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Ampyrone (4-Aminophenazone; 4-Aminoantipyrine) is a reversible and low-damage optical clearing agent and non-selective COX inhibitor based on UV absorption properties. Ampyrone can improve the optical transmittance of mouse skin and other tissues. Ampyrone can induce tissue refractive index matching by enhancing UV absorption, reduce light scattering, and achieve tissue transparency in vivo. Ampyrone reduces the synthesis of prostaglandin PGE2, thereby exerting anti-inflammatory, analgesic and antipyretic effects. Ampyrone inhibits DNA damage, cell apoptosis and immune cell phagocytosis induced by Doxorubicin (HY-15142A) and Cisplatin (HY-17394), etc., and participates in the regulation of toxicity in tumor chemotherapy .
1
1 Cited Publications
Cat. No.: HY-P4855
CAS No.: 376364-36-2
Target:
Research Areas:
1
Target:
Research Areas:
1
Category:
Other disease Metabolic Disease Endogenous metabolite Human Gut Microbiota Metabolites Flavonoids Isoflavanones Disease markers Phenols Polyphenols Disease Research Fields
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1
1
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ZEN-3694 (BET-IN-19) is an orally active BET inhibitor. ZEN-3694 regulates the function of BET proteins, thereby downregulating pathways involved in cell cycle regulation, ER signaling, AR signaling, AR splice variants, MYC, GR, cell growth, inflammation, and cellular immune responses. ZEN-3694 inhibits proliferation, induces apoptosis, reverses the upregulation of CDK6 and CCND1, restores cell cycle arrest, and inhibits CDK6 via miR-34a-5p. ZEN-3694 can be used in research related to HER2 breast cancer and metastatic castration-resistant prostate cancer .
Category:
Infection Alkaloids Microorganisms Other Alkaloids Marine natural products Disease Research Fields
Target:
Cat. No.: HY-P1120
CAS No.: 187986-17-0
Synonyms: WKYMVm-amide; W-Peptide
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
